C3orf52 and CCL26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C3orf52	CCL26
Description		chromosome 3 open reading frame 52	C-C motif chemokine ligand 26
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Cytokine Activity Protein Binding Chemokine Activity CCR3 Chemokine Receptor Binding CX3C Chemokine Receptor Binding Receptor Ligand Activity CCR Chemokine Receptor Binding
	Biological Process		Positive Regulation Of Endothelial Cell Proliferation Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Eosinophil Chemotaxis Positive Regulation Of Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494)	Carotid plaque burden ( 28282560) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
Interacting Genes		74 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FKBP7 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB GPX8 HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SLC10A1 SLC10A2 SLC10A6 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 UPK2 ZNRF3	24 interacting genes: APP C3orf52 CCL11 CCL13 CCL17 CCL2 CCL21 CCL28 CCL5 CCL8 CCR1 CCR3 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL9 PAX6 PF4 PF4V1 PPBP XCL1 XCL2
Entrez ID		79669	10344
HPRD ID		08018	05262
Ensembl ID		ENSG00000114529	ENSG00000006606
Uniprot IDs		Q5BVD1	Q9Y258
PDB IDs			1G2S 1G2T
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Bile Acid:sodium Symporter Activity Plasma Membrane Glutathione Peroxidase Activity Bile Acid And Bile Salt Transport Leukotriene-C4 Synthase Activity	Chemokine Activity Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Locomotion Antimicrobial Humoral Response Leukocyte Chemotaxis Humoral Immune Response Cytokine Activity Chemokine-mediated Signaling Pathway Leukocyte Migration Myeloid Leukocyte Migration Cell Migration Granulocyte Chemotaxis Cell Motility Killing Of Cells Of Another Organism Granulocyte Migration Inflammatory Response Defense Response To Symbiont Cell Killing Defense Response To Other Organism Immune Response Defense Response Immune System Process Cytokine-mediated Signaling Pathway Response To Other Organism Extracellular Space CXCR Chemokine Receptor Binding CCR Chemokine Receptor Binding Response To External Biotic Stimulus Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Leukocyte Migration Extracellular Region Regulation Of Leukocyte Migration Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Response To Stress Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Eosinophil Chemotaxis Regulation Of Cell Migration Positive Regulation Of Locomotion Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Eosinophil Migration Regulation Of Cell Motility Positive Regulation Of Monocyte Chemotaxis Regulation Of Locomotion Positive Regulation Of Calcium Ion Transport
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