JUND and ACTR3

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		JUND	ACTR3
Gene Name		jun D proto-oncogene	ARP3 actin-related protein 3 homolog (yeast)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Protein Complex	Golgi Membrane Podosome Cytosol Actin Filament Arp2/3 Protein Complex Cell-cell Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Hemidesmosome Excitatory Synapse Extracellular Vesicular Exosome
	Molecular Function	Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Ligand-dependent Nuclear Receptor Binding Enzyme Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding
	Biological Process	Osteoblast Development Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Aging Circadian Rhythm Response To Light Stimulus Response To Mechanical Stimulus Response To Organic Cyclic Compound Response To Lipopolysaccharide Response To Peptide Hormone Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Calcium Ion	Movement Of Cell Or Subcellular Component Establishment Or Maintenance Of Cell Polarity Axon Guidance Asymmetric Cell Division Response To Carbohydrate Positive Regulation Of Lamellipodium Assembly Meiotic Chromosome Movement Towards Spindle Pole Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Myosin II Filament Organization Innate Immune Response Response To Antibiotic Ephrin Receptor Signaling Pathway Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Filopodium Assembly Spindle Localization Cilium Morphogenesis
Pathways			EPHB-mediated forward signaling Axon guidance EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ACTR3 ATF3 BATF BCL6 BRCA1 COPS5 DDIT3 EP300 ESR1 FOS FOSB FOSL2 HINFP JDP2 LINC00461 MAPK1 MAPK3 MAPK8 MAPK9 MDM2 MEN1 NFE2L1 NFE2L2 PPARG RFWD2 SLC25A12 SMAD3 SMAD4 TBP	13 interactors: ACTR2 ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CDH1 CTTN HCLS1 JUND WASF2 WASF3 WASL
Entrez ID		3727	10096
HPRD ID		01304	05024
Ensembl ID		ENSG00000130522	ENSG00000115091
Uniprot IDs		P17535	B4DXW1 P61158
PDB IDs		3U86
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Cellular Macromolecule Biosynthetic Process Response To Abiotic Stimulus Macromolecule Biosynthetic Process RNA Metabolic Process Response To Organic Substance Response To Stress Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Biosynthetic Process Response To Lipid Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Stimulus Intracellular Signal Transduction Cell Death Death Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Response To Organic Cyclic Compound	Actin Filament Organization Actin Cytoskeleton Organization Actin Filament-based Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Ephrin Receptor Signaling Pathway Regulation Of Actin Filament-based Process Cytoskeleton Organization Phagocytosis Cell Projection Organization Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Development Regulation Of Cellular Component Organization Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Immune Response-regulating Cell Surface Receptor Signaling Pathway Endocytosis Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Organelle Organization Positive Regulation Of Actin Filament Polymerization Cell Morphogenesis Cell Differentiation Positive Regulation Of Protein Polymerization Immune Response-regulating Signaling Pathway Neuron Projection Development Cell Projection Morphogenesis Actin Nucleation Regulation Of Immune System Process Cell Part Morphogenesis Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Cellular Component Size Positive Regulation Of Protein Complex Assembly Neuron Development Positive Regulation Of Immune Response Neuron Projection Morphogenesis Organelle Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Actin Polymerization Or Depolymerization Neurogenesis
Tagcloud ?		acidophilia astrocyte axotomized chat choline cholinergic cresyl depressed die elicit fate ff fimbria fornix immunoreactive itfs krox lose medial microglial mystery ngfr parvalbumin septal septohippocampal transection transferase violet	actb anxa2 anxa6 canine cope dedifferentiation grade histologically hspa9 interesting kit mast mct mcts mutational noteworthy observable oncology paradox pdia3 proliferating proteome reflected tcp1a tcp1e transferrin tryptase tumours wdr1
Tagcloud (Difference) ?		acidophilia astrocyte axotomized chat choline cholinergic cresyl depressed die elicit fate ff fimbria fornix immunoreactive itfs krox lose medial microglial mystery ngfr parvalbumin septal septohippocampal transection transferase violet	actb anxa2 anxa6 canine cope dedifferentiation grade histologically hspa9 interesting kit mast mct mcts mutational noteworthy observable oncology paradox pdia3 proliferating proteome reflected tcp1a tcp1e transferrin tryptase tumours wdr1
Tagcloud (Intersection) ?