ITGB6 and FLNB

Number of citations of the paper that reports this interaction (PMID 11807098)
25

Data Source:
BioGRID (two hybrid)

		ITGB6	FLNB
Gene Name		integrin, beta 6	filamin B, beta
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integrin Complex External Side Of Plasma Membrane Receptor Complex Extracellular Vesicular Exosome	Stress Fiber Cytoplasm Cytosol Plasma Membrane Focal Adhesion Cell Cortex Actin Cytoskeleton Integral Component Of Membrane Z Disc Extracellular Vesicular Exosome
	Molecular Function	Virus Receptor Activity Integrin Binding	Actin Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Inflammatory Response Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Multicellular Organismal Development Response To Virus Viral Process Extracellular Matrix Organization	Cytoskeletal Anchoring At Plasma Membrane Signal Transduction Skeletal Muscle Tissue Development Cytokine-mediated Signaling Pathway Actin Cytoskeleton Organization Cell Differentiation
Pathways		Molecules associated with elastic fibres Elastic fibre formation ECM proteoglycans Integrin cell surface interactions	ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS		Nephropathy (idiopathic membranous) ( 21323541) Type 2 diabetes ( 20418489)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		8 interactors: FHL2 FLNA FLNB FN1 ITGAV MAPK1 TGFB1 VTN	17 interactors: ASB2 ATF7IP FBLIM1 FLNA GP1BA ITGB1 ITGB3 ITGB6 MLH1 NPHP1 PLEKHO1 PSEN1 PSEN2 RAD21 SMURF2 TRIM55 TSHR
Entrez ID		3694	2317
HPRD ID		00947	04543
Ensembl ID		ENSG00000115221	ENSG00000136068
Uniprot IDs		B4E2B8 C9JA97 E9PEE8 P18564	E7EN95 O75369
PDB IDs		1LH9	2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L
Enriched GO Terms of Interacting Partners?		Tissue Development Endoderm Development Blood Coagulation Hemostasis Cell Differentiation Endodermal Cell Differentiation Platelet Activation Regulation Of Body Fluid Levels Wound Healing Endoderm Formation Anatomical Structure Morphogenesis Response To Wounding Vesicle-mediated Transport Cell Morphogenesis Involved In Differentiation Platelet Degranulation Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Multicellular Organismal Development Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Anatomical Structure Development Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Vesicle-mediated Transport Cell Development Anatomical Structure Formation Involved In Morphogenesis Developmental Process Cell Morphogenesis Formation Of Primary Germ Layer Positive Regulation Of Peptidyl-threonine Phosphorylation ERK1 And ERK2 Cascade Regulation Of Protein Metabolic Process Cell Adhesion Cell-matrix Adhesion Regulation Of Cell Migration Regulation Of Endocytosis Gastrulation Regulation Of Cell Motility System Development Cell-substrate Adhesion Regulation Of Locomotion Cell Activation Regulation Of Cellular Component Movement MAPK Cascade Positive Regulation Of Transport Lipopolysaccharide-mediated Signaling Pathway Signal Transduction By Phosphorylation Substrate Adhesion-dependent Cell Spreading Cardiovascular System Development Negative Regulation Of Protein Metabolic Process	Cell Activation Cell Adhesion Single Organismal Cell-cell Adhesion Signal Transduction Cellular Response To Stimulus Signaling Cell Communication Viral Entry Into Host Cell Entry Into Host Cell Lymphocyte Activation Cell Junction Assembly Regulation Of Peptidyl-tyrosine Phosphorylation Single-organism Behavior Cell Development Leukocyte Activation Amyloid Precursor Protein Catabolic Process Regulation Of Cellular Process Response To Stimulus Neuron Development Cell Fate Specification Behavior Interaction With Host Embryonic Morphogenesis Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Cell Surface Receptor Signaling Pathway Homotypic Cell-cell Adhesion Leukocyte Differentiation Neuron Differentiation Integrin-mediated Signaling Pathway Tissue Development Cell Projection Organization Immune System Development Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Signal Transduction Cell Differentiation Heterotypic Cell-cell Adhesion Regulation Of Epidermal Growth Factor-activated Receptor Activity Response To Stress Developmental Process Leukocyte Activation Involved In Immune Response B Cell Activation Blood Coagulation Cell-matrix Adhesion Hemostasis Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?		adhesion agilent bioinformatics cdc14a cdkn1c cdkn2a clustering col6a3 ctnna3 cycles david differentially distinctly dysregulated experiment focal folds go hoxb4 hyperplastic oligonucletide pairs regulated repeating resources scar scars tgfbeta1 twice	actionable algorithms asf1 assuming candidates distinguishing driver genomes grm1 hcf1 hierarchically interpreting involve machinery modules neutral organized passenger pou2f1 precisely presents prkcz psnv psnvs snvs thousands uncovered unexpectedly ways
Tagcloud (Difference) ?		adhesion agilent bioinformatics cdc14a cdkn1c cdkn2a clustering col6a3 ctnna3 cycles david differentially distinctly dysregulated experiment focal folds go hoxb4 hyperplastic oligonucletide pairs regulated repeating resources scar scars tgfbeta1 twice	actionable algorithms asf1 assuming candidates distinguishing driver genomes grm1 hcf1 hierarchically interpreting involve machinery modules neutral organized passenger pou2f1 precisely presents prkcz psnv psnvs snvs thousands uncovered unexpectedly ways
Tagcloud (Intersection) ?