INPP5A and TUBGCP2

		INPP5A	TUBGCP2
Description		inositol polyphosphate-5-phosphatase A	tubulin gamma complex component 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Cell Projection	Spindle Pole Gamma-tubulin Complex Nucleoplasm Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Cytoplasmic Microtubule Membrane Ciliary Basal Body
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity PH Domain Binding Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Phosphate-containing Compound Metabolic Process Organophosphate Metabolic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Dephosphorylation Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration Microtubule Nucleation Brain Development Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		Synthesis of IP2, IP, and Ins in the cytosol	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Gait speed in old age ( 28077804) Heel bone mineral density ( 28869591 30598549) Migraine ( 27182965) Primary sclerosing cholangitis ( 27992413) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 30275531)	Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)
Interacting Genes		3 interacting genes: PLEK TEAD2 YWHAZ	4 interacting genes: CEBPA KIF14 PCNT UBC
Entrez ID		3632	10844
HPRD ID		02521	18245
Ensembl ID		ENSG00000068383	ENSG00000130640
Uniprot IDs		Q14642	Q53EQ3 Q9BSJ2
PDB IDs			6V6B 6V6S 6X0V 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 8Q62 8RX1 8VRD 8VRJ 8VRK 9H9P
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Diameter Protein Secretion By Platelet Negative Regulation Of Inositol Phosphate Biosynthetic Process Phospholipase C-inhibiting G Protein-coupled Receptor Signaling Pathway Synaptic Target Recognition Tube Formation Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Platelet Degranulation Golgi Reassembly TEAD-YAP Complex Lateral Mesoderm Development Phosphatase Activator Activity Phosphoserine Residue Binding Thrombin-activated Receptor Signaling Pathway Positive Regulation Of Integrin Activation Positive Regulation Of Actin Filament Depolymerization Positive Regulation Of Platelet Activation Regulation Of Lysosome Organization Golgi Localization Establishment Of Golgi Localization Animal Organ Development Notochord Development Paraxial Mesoderm Development Microtubule Minus-end Binding Gamma-tubulin Complex Organelle Localization Positive Regulation Of Protein Depolymerization Intracellular Signal Transduction Regulation Of Integrin Activation Antibacterial Innate Immune Response
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