INPP5A

Gene Name		inositol polyphosphate-5-phosphatase, 40kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity Protein Binding PH Domain Binding Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
	Biological Process	Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation
Pathways		Synthesis of IP2, IP, and Ins in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: PLEK YWHAZ
Entrez ID		3632
HPRD ID		02521
Ensembl ID		ENSG00000068383
Uniprot IDs		Q14642 Q8N6C1
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Positive Regulation Of Inositol-polyphosphate 5-phosphatase Activity Negative Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Cell Diameter Phospholipase C-inhibiting G-protein Coupled Receptor Signaling Pathway Exocytosis Protein Secretion By Platelet Positive Regulation Of Organelle Organization Golgi Reassembly Blood Coagulation Hemostasis Positive Regulation Of Integrin Activation Histamine Secretion By Mast Cell Secretion By Cell Establishment Of Golgi Localization Golgi Inheritance Positive Regulation Of Platelet Activation Regulation Of Body Fluid Levels Wound Healing Negative Regulation Of Calcium-mediated Signaling Secretion Histamine Secretion Cell Activation Regulation Of Integrin Activation Response To Wounding Thrombin Receptor Signaling Pathway Histamine Transport Positive Regulation Of Actin Filament Depolymerization Golgi Localization Regulation Of Organelle Organization Positive Regulation Of Protein Depolymerization Mast Cell Degranulation Production Of Molecular Mediator Involved In Inflammatory Response Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Mast Cell Mediated Immunity Cortical Actin Cytoskeleton Organization Lysosome Localization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mast Cell Activation Protein Kinase C Signaling Positive Regulation Of Protein Complex Disassembly Cortical Cytoskeleton Organization Regulation Of Platelet Activation Positive Regulation Of Phosphatase Activity Positive Regulation Of Blood Coagulation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Leukocyte Degranulation Ruffle Organization Platelet Aggregation Positive Regulation Of Coagulation
Tagcloud ?		accumulate alterations anaplastic astrocytoma consequence correlations cps1 genomic glial glioblastoma glioma gp2 htr4 implies instability itgb1 kcng2 kir3dl3 lhfpl3 p16 passenger pathogenesis pde4d predominantly pros1 pten seem sgcg subtypes