AQP5 and GLRX

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AQP5	GLRX
Gene Name		aquaporin 5	glutaredoxin (thioltransferase)
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Microvillus Basal Plasma Membrane Apical Plasma Membrane Extracellular Vesicular Exosome	Nucleus Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Water Channel Activity Glycerol Channel Activity	Electron Carrier Activity Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity
	Biological Process	Water Transport Excretion Cellular Water Homeostasis Carbon Dioxide Transport Glycerol Transport Pancreatic Juice Secretion Ion Transmembrane Transport Odontogenesis Saliva Secretion Camera-type Eye Morphogenesis Transmembrane Transport	Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process Cell Redox Homeostasis Positive Regulation Of Membrane Potential Nucleobase-containing Small Molecule Metabolic Process Oxidation-reduction Process Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Passive transport by Aquaporins Aquaporin-mediated transport	Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: GLRX HNRNPK KRT31 KRT40 MDFI NOTCH2NL WNT2	7 interactors: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1
Entrez ID		362	2745
HPRD ID		02706	02707
Ensembl ID			ENSG00000173221
Uniprot IDs		P55064	P35754
PDB IDs		3D9S	1B4Q 1JHB
Enriched GO Terms of Interacting Partners?		Protein Deglutathionylation Embryonic Placenta Development Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Placenta Development Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Iris Morphogenesis Atrial Cardiac Muscle Tissue Morphogenesis Lung Induction Regulation Of Wnt Signaling Pathway Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Neuron Death Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Positive Regulation Of Endopeptidase Activity Odontogenesis Positive Regulation Of Peptidase Activity Fumarate Metabolic Process Regulation Of Protein Kinase Activity Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway L-kynurenine Metabolic Process Platelet-derived Growth Factor Receptor-beta Signaling Pathway Carbon Dioxide Transport Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Glutamate Catabolic Process Pancreatic Juice Secretion Glial Cell Apoptotic Process Negative Regulation Of Kinase Activity Protein Processing Regulation Of Apoptotic DNA Fragmentation Aspartate Metabolic Process Saliva Secretion Regulation Of Protein Phosphorylation Regulation Of Neuron Death Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Glycerol Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Phosphorylation Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Kynurenine Metabolic Process Dicarboxylic Acid Catabolic Process Polyol Transport Cellular Water Homeostasis Apoptotic Signaling Pathway
Tagcloud ?		accordingly aquaporin basis categorize curative ebc epidermal immunohistochemistry intensity marker mcf microarray multivariate overexpressed percentage pr progesterone prognostic prominent score scored staining stating strong sum surgery unfavorable univariate weak	affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous
Tagcloud (Difference) ?		accordingly aquaporin basis categorize curative ebc epidermal immunohistochemistry intensity marker mcf microarray multivariate overexpressed percentage pr progesterone prognostic prominent score scored staining stating strong sum surgery unfavorable univariate weak	affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous
Tagcloud (Intersection) ?