TMEM86A and PDZK1IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM86A	PDZK1IP1
Description		transmembrane protein 86A	PDZK1 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process
Pathways
Drugs
Diseases
GWAS		Ovarian reserve ( 22116950)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		48 interacting genes: AQP2 AQP3 BCL2L13 CD79A CISD2 CNR2 COQ9 CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 FXYD3 GJB4 GJB5 GJC1 GORAB GPR37L1 GPX8 HAVCR2 KASH5 KCNA1 LHFPL5 LMNA MS4A2 MUC1 NCAPH2 PDZK1IP1 PGRMC2 PI16 REEP4 RIC3 RNF185 SCN3B SLC10A6 SLC18A1 SLC30A2 SLC35H1 SLC39A2 SSMEM1 THAP4 TIMMDC1 TMEM31 TMPRSS2 TYROBP	77 interacting genes: AGR3 AIG1 APOA2 APOD AQP2 AQP6 ARL13B ASGR1 C14orf180 C2CD2L CD81 CES1 CLDN19 COPS6 CYB5B CYBC1 EMC6 ERG28 FAM3C FCER1G GALNT15 GAST GIMAP5 GRM2 GYPA HMOX1 ICMT IGFBP5 JAGN1 LEPROTL1 LHFPL5 MIP MYADM MYADML2 NSG1 NUMB PDZK1 PEX16 PGAP2 PLP2 PLPP4 PLPP6 PMP22 RPRM RTP2 SDCBP SFTPC SFXN2 SLC22A1 SLC22A2 SLC35B1 SLC35B4 STRIT1 STX12 THBD TMEM101 TMEM107 TMEM109 TMEM11 TMEM140 TMEM14A TMEM14B TMEM14C TMEM203 TMEM39B TMEM65 TMEM86A TMEM97 TNFRSF10C TRARG1 TRIM54 TSPO2 UPK1B UTP14A VAMP3 YIPF6 ZDHHC17
Entrez ID		144110	10158
HPRD ID		08292	06211
Ensembl ID		ENSG00000151117	ENSG00000162366
Uniprot IDs		Q8N2M4	Q13113
PDB IDs			7VSI 7WMV 7YNI 7YNJ 7YNK 8HB0 8HDH 8HEZ 8HG7 8HIN
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding Connexin Complex Gap Junction Channel Activity Gap Junction Glycerol Transmembrane Transport Monoatomic Ion Transport Renal Water Transport Endoplasmic Reticulum Polyol Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential Transport Vesicle Membrane	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Localization Within Membrane Organic Hydroxy Compound Transport Protein Binding Cholesterol Binding Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Protein Localization To Membrane Serotonin Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Cellular Response To Lipoprotein Particle Stimulus Quaternary Ammonium Group Transport Water Channel Activity Cellular Localization Organic Cation Transport Putrescine Transmembrane Transporter Activity Lipid Transport Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Transmembrane Transport Water Transport Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Protein Localization To Plasma Membrane Cholesterol Transport Monoamine Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Cellular Response To Low-density Lipoprotein Particle Stimulus Carnitine Transmembrane Transport Carnitine Transport Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Sterol Transport Regulation Of Transport Renal Water Transport Fluid Transport Heme Metabolic Process Serotonin Uptake Norepinephrine Transport Neutrophil Differentiation
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