KRT4 and C14orf119

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT4	C14orf119
Description		keratin 4	chromosome 14 open reading frame 119
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intermediate Filament Cell Surface Keratin Filament Intermediate Filament Cytoskeleton	Mitochondrion Cytosol
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Cytoskeleton Organization Epithelial Cell Differentiation Keratinization Intermediate Filament Organization Negative Regulation Of Epithelial Cell Proliferation
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		White sponge nevus
GWAS
Interacting Genes		22 interacting genes: C14orf119 CCDC57 CEP57 KIFC3 KRT14 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 PPP1R13B TRIM54 TUBGCP4	56 interacting genes: ACTN4 ARID3C ARID5A AUNIP BEND7 BIN3 C1QTNF1 CCND3 CDC14A CHMP1A CLPP CTAG1A CTAG1B DDIT4L DECR2 DYNLL1 DYNLL2 HES6 HLX HMG20B ITGB3BP KHDC4 KRT4 KRT78 KRTAP13-3 LASP1 LDB2 LENG1 LRRCC1 MEOX1 MORN3 MYF5 NIF3L1 NME4 NRIP3 NUP54 NUP62 PBX4 PHACTR1 PINX1 RAB3IL1 REL RHOU RND3 RNF4 RPIA SMCP SNX8 SSX4 SSX4B STN1 SYCP3 TEX35 TLE5 UBXN11 WASHC1
Entrez ID		3851	55017
HPRD ID		00478	16595
Ensembl ID		ENSG00000170477	ENSG00000179933
Uniprot IDs		P19013	Q9NWQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Epithelial Cell Differentiation Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Structural Constituent Of Cytoskeleton Cell Differentiation Cellular Developmental Process Cytosol Hair Cycle Developmental Process Hair Follicle Morphogenesis Epidermis Development Hair Cycle Process Cell Periphery Microtubule Nucleation Centriolar Satellite Gamma-tubulin Binding Microtubule Intermediate Filament Polymerization Sulfite Oxidase Activity Protein Binding Intermediate Filament Polymerization Or Depolymerization Negative Regulation Of Entry Of Bacterium Into Host Cell Zonula Adherens Maintenance Terminal Web Molybdenum Ion Binding Keratinization Scaffold Protein Binding Microtubule Binding Molybdopterin Cofactor Binding	Protein Binding
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