KRT4 and KRT28

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT4	KRT28
Description		keratin 4	keratin 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intermediate Filament Cell Surface Keratin Filament Intermediate Filament Cytoskeleton	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Cytoskeleton Organization Epithelial Cell Differentiation Keratinization Intermediate Filament Organization Negative Regulation Of Epithelial Cell Proliferation	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		White sponge nevus
GWAS			Cognitive decline rate in late mild cognitive impairment ( 26252872) Glucose homeostasis traits ( 25524916)
Interacting Genes		22 interacting genes: C14orf119 CCDC57 CEP57 KIFC3 KRT14 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 PPP1R13B TRIM54 TUBGCP4	23 interacting genes: ABI3 CCDC196 DEUP1 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT76 KRT79 KRT8 KRT80 KRT81 KRT86 NUP58 UCHL5 USHBP1 WASHC1
Entrez ID		3851	162605
HPRD ID		00478	17245
Ensembl ID		ENSG00000170477	ENSG00000173908
Uniprot IDs		P19013	Q7Z3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Epithelial Cell Differentiation Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Structural Constituent Of Cytoskeleton Cell Differentiation Cellular Developmental Process Cytosol Hair Cycle Developmental Process Hair Follicle Morphogenesis Epidermis Development Hair Cycle Process Cell Periphery Microtubule Nucleation Centriolar Satellite Gamma-tubulin Binding Microtubule Intermediate Filament Polymerization Sulfite Oxidase Activity Protein Binding Intermediate Filament Polymerization Or Depolymerization Negative Regulation Of Entry Of Bacterium Into Host Cell Zonula Adherens Maintenance Terminal Web Molybdenum Ion Binding Keratinization Scaffold Protein Binding Microtubule Binding Molybdopterin Cofactor Binding	Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Extracellular Exosome Cytosol Structural Constituent Of Cytoskeleton Epidermis Development Peptide Cross-linking Intermediate Filament Polymerization
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