IGFBP7 and IGF1

  • Number of citations of the paper that reports this interaction (PMID 8939990)
  • 29
  • Data Source:
  • HPRD (in vitro)

IGFBP7

IGF1

Gene Name insulin-like growth factor binding protein 7 insulin-like growth factor 1 (somatomedin C)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related macular degeneration ( 21909106)
  • Fasting glucose-related traits ( 20081858)
  • Fasting insulin-related traits ( 20081858)
  • Fasting insulin-related traits (interaction with BMI) ( 22581228)
  • Height ( 19893584 20189936)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions 11 interactors: CCL21 CCL5 CHMP3 CXCL10 IGF1 IGF2 INHBA INS RBBP8 SDC1 VEGFA 16 interactors: CTSB E2F1 IDE IGF1R IGFALS IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IGSF1 NOV TF WISP2
Entrez ID 3490 3479
HPRD ID 04183 00936
Ensembl ID ENSG00000163453 ENSG00000017427
Uniprot IDs Q16270 P05019 Q13429 Q59GC5 Q5U743
PDB IDs 1B9G 1BQT 1GF1 1GZR 1GZY 1GZZ 1H02 1H59 1IMX 1PMX 1TGR 1WQJ 2DSP 2DSQ 2DSR 2GF1 3GF1 3LRI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
achieve  additive  aza  dc  demethylating  demethylation  deoxycytidine  difficult  dual  efficiently  epigenetic  exists  ezh2  focusing  gsk126  h3k27me3  limitation  methylated  methylation  modification  modifications  overcome  preferentially  promising  re  sfrp1  trimethylation  utilized  xenograft 
alphair3  augmenting  blastocyst  blastocysts  cytoplasm  embryo  embryos  entirely  fallopian  immunocytochemistry  immunoreactive  implantation  inner  intense  ivf  lining  maternal  maternally  midcycle  mimicking  paracrine  preimplantation  reproductive  supplementation  transcripts  tubal  tube  uterus 
Tagcloud (Difference) ?
achieve  additive  aza  dc  demethylating  demethylation  deoxycytidine  difficult  dual  efficiently  epigenetic  exists  ezh2  focusing  gsk126  h3k27me3  limitation  methylated  methylation  modification  modifications  overcome  preferentially  promising  re  sfrp1  trimethylation  utilized  xenograft 
alphair3  augmenting  blastocyst  blastocysts  cytoplasm  embryo  embryos  entirely  fallopian  immunocytochemistry  immunoreactive  implantation  inner  intense  ivf  lining  maternal  maternally  midcycle  mimicking  paracrine  preimplantation  reproductive  supplementation  transcripts  tubal  tube  uterus 
Tagcloud (Intersection) ?