IGFBP2 and INO80B

Number of citations of the paper that reports this interaction (PMID 19095771)
6

Data Source:
BioGRID (pull down, affinity chromatography technology)

		IGFBP2	INO80B
Gene Name		insulin-like growth factor binding protein 2, 36kDa	INO80 complex subunit B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Ino80 Complex
	Molecular Function	Protein Binding Insulin-like Growth Factor I Binding Insulin-like Growth Factor II Binding	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Cell Growth Signal Transduction Female Pregnancy Aging Response To Nutrient Response To Mechanical Stimulus Response To Lithium Ion Response To Estradiol Response To Retinoic Acid Cellular Response To Hormone Stimulus Positive Regulation Of Activated T Cell Proliferation Response To Drug Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Glucocorticoid	DNA Repair DNA Recombination Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: GSDMB IGF1 IGF2 INO80B KLK2 TF	5 interactors: CD81 IGFBP2 PNMA1 SSX2IP UIMC1
Entrez ID		3485	83444
HPRD ID		00898	17110
Ensembl ID		ENSG00000115457	ENSG00000115274
Uniprot IDs		C9JMY1 P18065	Q9C086
PDB IDs		2H7T
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Exocrine Pancreas Development Positive Regulation Of Glycogen Biosynthetic Process Platelet Activation Positive Regulation Of Activated T Cell Proliferation Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Metabolic Process Regulation Of Activated T Cell Proliferation Regulation Of Glycogen Metabolic Process Exocytosis Positive Regulation Of Mitotic Nuclear Division Blood Coagulation Hemostasis Exocrine System Development Secretion By Cell Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of T Cell Proliferation Regulation Of Body Fluid Levels Wound Healing Pancreas Development Secretion Regulation Of Glucose Metabolic Process Cell Activation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Response To Wounding Regulation Of Mitotic Nuclear Division Regulation Of Protein Kinase B Signaling Positive Regulation Of Cell Division Regulation Of T Cell Proliferation Digestive System Development Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Prostate Gland Stromal Morphogenesis Glycolate Metabolic Process Positive Regulation Of T Cell Activation Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Oocyte Development Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Cycle Process Striated Muscle Cell Differentiation Positive Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Division Positive Regulation Of Myoblast Proliferation Myoblast Proliferation	Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Histone H2A K63-linked Deubiquitination Receptor-mediated Virion Attachment To Host Cell Intraciliary Transport Involved In Cilium Morphogenesis Virion Attachment To Host Cell Positive Regulation Of Cell Activation Adhesion Of Symbiont To Host Regulation Of Lymphocyte Activation Protein K63-linked Deubiquitination Regulation Of Cell Activation Histone Deubiquitination Positive Regulation Of Activated T Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Tagcloud ?		anabolic astrocytes carotid cerebral extremely hemisphere hypoxia hypoxic immature immediate impending insult insults ipsilateral ischemia ischemic ligation messenger myelinogenesis perinatal permanent perturbations pleiotrophic pronounced recovery thalamus vulnerability vulnerable	2p13 absolutely consequence drastically eclampsia elucidation evolved founder genetics guided hemochorial icelandic linkage mer multifactorial paralogous pfam14465 placentally placentation pools premise prioritized pumillio rs34174194 trophoblast uguanaag utr uugucug winged
Tagcloud (Difference) ?		anabolic astrocytes carotid cerebral extremely hemisphere hypoxia hypoxic immature immediate impending insult insults ipsilateral ischemia ischemic ligation messenger myelinogenesis perinatal permanent perturbations pleiotrophic pronounced recovery thalamus vulnerability vulnerable	2p13 absolutely consequence drastically eclampsia elucidation evolved founder genetics guided hemochorial icelandic linkage mer multifactorial paralogous pfam14465 placentally placentation pools premise prioritized pumillio rs34174194 trophoblast uguanaag utr uugucug winged
Tagcloud (Intersection) ?