FAM174A and BET1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM174A	BET1
Description		family with sequence similarity 174 member A	Bet1 golgi vesicular membrane trafficking protein
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cis-Golgi Network Membrane Transport Vesicle SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding	SNAP Receptor Activity Protein Binding
	Biological Process		Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus
Pathways			COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)	Aging ( 22773346) Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) BRCA1/2-negative high-risk breast cancer ( 30323354) Obesity-related traits ( 23251661) World class endurance athleticism ( 26824906)
Interacting Genes		36 interacting genes: ANKRD46 ARLN BET1 BNIP1 C14orf180 CCDC167 CMTM7 DEFB127 ERG28 FKBP8 GIMAP1 GIMAP5 GOSR2 HMOX1 LCK PLLP PLPP6 RTP2 SEC22A SEC22B SERP1 SLC30A2 SMCO4 SMIM1 STX7 STX8 TMEM11 TMEM203 TMEM222 TMEM239 TMEM243 TMEM42 TMEM65 TREX1 VAMP3 VAPB	57 interacting genes: ADORA2A ANKS6 AQP6 ASGR2 ASZ1 BCL2L13 BIK CD74 CD79A CGRRF1 CISD2 CLDN7 CLEC10A CRB3 CREB3L1 CYB561 CYB5R3 CYBC1 ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FAM9B FKBP7 GPR152 GPX8 JAGN1 KASH5 KCNJ6 LYPD5 MAGEA6 MFF MGST3 NAPB PTGES REEP4 RETREG3 SAR1A SLC26A6 SLC35H1 SLC7A14 SNCA SNTG2 SSMEM1 STX1A STX1B STX2 STX4 STX5 TMCO5A TMEM237 TMEM35A TMEM52B TMEM80 TMX2 USHBP1
Entrez ID		345757	10282
HPRD ID		18260	16107
Ensembl ID		ENSG00000174132	ENSG00000105829
Uniprot IDs		Q8TBP5	O15155 Q53XK0
PDB IDs			3EGX
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity Membrane SNARE Complex Endoplasmic Reticulum Membrane Membrane Fusion Endoplasmic Reticulum Membrane Organization Organelle Membrane Fusion Organelle Fusion Golgi Vesicle Transport Vesicle Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Transport Vesicle Chloride Channel Inhibitor Activity Vesicle-mediated Transport Secretory Vesicle Protein Binding Endomembrane System Establishment Of Protein Localization Vesicle Docking SNARE Binding Endoplasmic Reticulum Membrane Organization Intracellular Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cellular Localization	Membrane Endoplasmic Reticulum Membrane SNARE Binding SNAP Receptor Activity Positive Regulation Of Neurotransmitter Secretion Protein Binding SNARE Complex Endoplasmic Reticulum Vesicle Docking Regulation Of Synaptic Vesicle Priming Organelle Localization By Membrane Tethering SNARE Complex Assembly Membrane Docking Vesicle Fusion Organelle Membrane Fusion Glutathione Peroxidase Activity Exocytosis Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Mitochondrial Outer Membrane Organelle Fusion Presynaptic Active Zone Membrane Vesicle-mediated Transport Positive Regulation Of Synaptic Transmission Cornified Envelope Assembly Membrane Fusion Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Secretion Fucose Binding Prostanoid Metabolic Process Endomembrane System Unsaturated Fatty Acid Metabolic Process Regulation Of Catecholamine Secretion Secretion Neurotransmitter Transport Unsaturated Fatty Acid Biosynthetic Process Response To Type II Interferon Secretion By Cell Mitochondrial Membrane Icosanoid Biosynthetic Process Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Secretion By Cell Vesicle Fusion To Plasma Membrane Regulation Of Norepinephrine Secretion Vesicle Organization Synaptic Vesicle Docking Positive Regulation Of Secretion Organelle Localization Membrane Assembly Synaptic Transmission, Dopaminergic
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