FAM174A and DEFB127

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM174A	DEFB127
Description		family with sequence similarity 174 member A	defensin beta 127
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Extracellular Region
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Defense Response Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways			Beta defensins Defensins
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)	Coronary artery disease in type 1 diabetes ( 32077919)
Interacting Genes		36 interacting genes: ANKRD46 ARLN BET1 BNIP1 C14orf180 CCDC167 CMTM7 DEFB127 ERG28 FKBP8 GIMAP1 GIMAP5 GOSR2 HMOX1 LCK PLLP PLPP6 RTP2 SEC22A SEC22B SERP1 SLC30A2 SMCO4 SMIM1 STX7 STX8 TMEM11 TMEM203 TMEM222 TMEM239 TMEM243 TMEM42 TMEM65 TREX1 VAMP3 VAPB	14 interacting genes: AQP6 ASZ1 AURKAIP1 BCL2L13 CD79A CPLX4 EBP FAM174A FCER1G LMNA MMGT1 PIANP SLC71A2 TFEC
Entrez ID		345757	140850
HPRD ID		18260	10877
Ensembl ID		ENSG00000174132	ENSG00000088782
Uniprot IDs		Q8TBP5	Q9H1M4
PDB IDs
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity Membrane SNARE Complex Endoplasmic Reticulum Membrane Membrane Fusion Endoplasmic Reticulum Membrane Organization Organelle Membrane Fusion Organelle Fusion Golgi Vesicle Transport Vesicle Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Transport Vesicle Chloride Channel Inhibitor Activity Vesicle-mediated Transport Secretory Vesicle Protein Binding Endomembrane System Establishment Of Protein Localization Vesicle Docking SNARE Binding Endoplasmic Reticulum Membrane Organization Intracellular Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cellular Localization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?