ID1 and ASCL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ID1	ASCL3
Description		inhibitor of DNA binding 1	achaete-scute family bHLH transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Chromatin Nucleus Transcription Regulator Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Dimerization Activity Transcription Regulator Inhibitor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Endothelial Cell Morphogenesis Apoptotic Process Transforming Growth Factor Beta Receptor Signaling Pathway Heart Development Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Neuron Differentiation BMP Signaling Pathway Protein Destabilization Collagen Metabolic Process Regulation Of MAPK Cascade Negative Regulation Of DNA-binding Transcription Factor Activity Blood Vessel Endothelial Cell Migration Negative Regulation Of Osteoblast Differentiation Regulation Of Angiogenesis Negative Regulation Of DNA-templated Transcription Response To Antibiotic Rhythmic Process Blood Vessel Morphogenesis Lung Morphogenesis Lung Vasculature Development Endothelial Cell Apoptotic Process Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Endothelial Cell Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Tissue Homeostasis Regulation Of Transcription By RNA Polymerase II Salivary Gland Development Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Epithelium Development Sensory Epithelium Regeneration
Pathways		Oncogene Induced Senescence NGF-stimulated transcription Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)	Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		26 interacting genes: APPL1 ASCL3 CASK COPB1 DNMT3L ELK1 ELK4 GATA4 HES1 IFI16 IKBKG MSGN1 MYF5 MYF6 MYOD1 MYOG PSMD4 RNF4 RUNX1T1 SUV39H1 TCF12 TCF3 TCF4 TRIM55 TRIM63 UBC	7 interacting genes: APP GTF2A1L HEMK1 ID1 MYOD1 TCF3 VPS37C
Entrez ID		3397	56676
HPRD ID		08980	18523
Ensembl ID		ENSG00000125968	ENSG00000176009
Uniprot IDs		P41134	Q9NQ33
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription By RNA Polymerase II E-box Binding Protein Dimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Macromolecule Metabolic Process DNA Binding Chromatin Nucleus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Muscle Cell Fate Commitment Positive Regulation Of Metabolic Process Cell Fate Commitment Sequence-specific Double-stranded DNA Binding Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression DNA-binding Transcription Factor Activity RNA Polymerase II Transcription Regulator Complex Regulation Of Skeletal Muscle Tissue Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Anterior/posterior Pattern Specification Regulation Of Striated Muscle Tissue Development Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Muscle Organ Development Regulation Of Myotube Differentiation Positive Regulation Of Myoblast Differentiation Regulation Of Metabolic Process Somitogenesis Animal Organ Development Cell Differentiation Regulation Of Macromolecule Metabolic Process Tissue Regeneration Segmentation Muscle Organ Development	Protein Dimerization Activity BHLH Transcription Factor Binding Amyloid-beta Complex Growth Cone Lamellipodium DNA Binding Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Euchromatin E-box Binding Cis-regulatory Region Sequence-specific DNA Binding Protein-glutamine N-methyltransferase Activity Peptide Chain Release Factor N(5)-glutamine Methyltransferase Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Neuron Differentiation Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Macromolecule Biosynthetic Process Myoblast Fate Determination Skeletal Muscle Fiber Adaptation Negative Regulation Of Myoblast Proliferation Vitamin D Response Element Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Cell Differentiation Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Biosynthetic Process Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of SnRNA Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Tissue Regeneration Myotube Differentiation Involved In Skeletal Muscle Regeneration Transcription Factor TFIIA Complex N-methyltransferase Activity Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of RNA Biosynthetic Process
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