CD300E and CTXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD300E	CTXN3
Description		CD300e molecule	cortexin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding	Protein Binding
	Biological Process	Immune System Process Signal Transduction Regulation Of Innate Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690)	Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		4 interacting genes: CTXN3 STX8 TRARG1 TYROBP	59 interacting genes: ADGRG3 AQP6 AQP9 ATP1B3 BIK BTN2A1 CD300E CD53 CD79A CERS4 CLDN14 CLEC17A CLEC7A CLRN1 COQ9 CPLX4 CREB3L1 CTLA4 EDA ERGIC3 FAM209A FFAR3 FUT7 GJA8 GJB1 GJB5 GPR152 GPR42 GPR61 IFNLR1 KASH5 KIR3DL3 KLRC1 LAPTM4B LDLRAD1 LHFPL5 LSMEM2 MFF MGST2 MTIF3 NCAPH2 OPRD1 OPRM1 PACC1 PLPP5 PVR SCN3B SLC10A2 SPACA1 STOM TLCD4 TM4SF19 TMEM106C TMEM167B TMEM179B TMEM31 TMPRSS2 TMX2 TSPAN12
Entrez ID		342510	613212
HPRD ID		17158	18888
Ensembl ID		ENSG00000186407	ENSG00000205279
Uniprot IDs		B4E0V9 Q496F6	Q4LDR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Osteoclast Development Microglial Cell Activation Involved In Immune Response Positive Regulation Of Microglial Cell Mediated Cytotoxicity Vesicle-mediated Transport Positive Regulation Of Receptor Localization To Synapse Stimulatory Killer Cell Immunoglobulin-like Receptor Signaling Pathway Positive Regulation Of Macrophage Fusion Negative Regulation Of Transforming Growth Factor Beta1 Production Endomembrane System Vesicle Fusion Endosomal Transport Organelle Membrane Fusion Membrane Fusion Organelle Fusion Glucose Import In Response To Insulin Stimulus Chloride Channel Inhibitor Activity T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Vesicle Organization Regulation Of Osteoclast Development Neutrophil Activation Involved In Immune Response Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Transforming Growth Factor Beta Production Vesicle Fusion To Plasma Membrane Endosome To Plasma Membrane Protein Transport Negative Regulation Of B Cell Proliferation Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Interleukin-10 Production Macrophage Activation Involved In Immune Response Regulation Of Superoxide Anion Generation Microglial Cell Activation Cellular Response To Lectin Regulation Of Receptor Localization To Synapse Positive Regulation Of Superoxide Anion Generation Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of Natural Killer Cell Activation Regulation Of Superoxide Metabolic Process Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Amyloid-beta Clearance Apoptotic Cell Clearance Neutrophil Activation Positive Regulation Of Protein Localization To Cell Surface Early Endosome To Late Endosome Transport Intracellular Protein Transport D-glucose Transmembrane Transport D-glucose Import Negative Regulation Of B Cell Activation Leukocyte Activation Involved In Inflammatory Response Hexose Transmembrane Transport Membrane Organization SNAP Receptor Activity	Membrane Plasma Membrane Protein Binding PH-gated Chloride Channel Activity Connexin Complex Gap Junction Channel Activity Gap Junction Immune Response-activating Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity G Protein-coupled Receptor Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway Immune System Process Immune Response-regulating Signaling Pathway
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