ANKRD33 and TRIM59

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ANKRD33	TRIM59
Description		ankyrin repeat domain 33	tripartite motif containing 59
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intraciliary Transport Particle B
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Skeletal Muscle Cell Differentiation	Protein Ubiquitination Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Host-mediated Suppression Of Symbiont Invasion
Pathways
Drugs
Diseases
GWAS		Energy intake ( 30071075) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Serum uric acid levels ( 30993211)	Alanine aminotransferase levels ( 33547301) Alcohol use disorder (total score) ( 30336701) Aspartate aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		11 interacting genes: ANKRD11 BFSP2 GPSM3 HPCAL4 KLHL42 MBD3 SDCBP TLX3 TRIM59 UBQLN2 USHBP1	29 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KEAP1 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM PIN1 PKNOX1 PLLP RASSF3 RHOU SEC22A SNAP47 SYVN1 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22
Entrez ID		341405	286827
HPRD ID		12465	15568
Ensembl ID		ENSG00000167612	ENSG00000213186
Uniprot IDs		Q0VAA8 Q5K617 Q7Z3H0	Q8IWR1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Receptor Internalization Negative Regulation Of Receptor-mediated Endocytosis	Nuclear Estrogen Receptor Activity SNAP Receptor Activity Negative Regulation Of Response To Oxidative Stress
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