GPSM1 and RIBC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPSM1	RIBC1
Description		G protein signaling modulator 1	RIB43A domain with coiled-coils 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Cell Cortex Membrane Protein-containing Complex	Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding GTPase Regulator Activity	Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Flagellated Sperm Motility
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Myocardial infarction ( 33532862) Offspring birth weight ( 31043758) Type 2 diabetes ( 23945395 32499647 31118516 30718926 30297969 29632382 28869590 26818947) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)	Bipolar disorder ( 31043756)
Interacting Genes		28 interacting genes: BHLHE40 CCDC158 CTDSP1 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 FXR2 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1	25 interacting genes: ATP6V0D2 BORCS6 CCNC EMILIN1 GOLGA2 GPSM1 HSF2BP KRT15 KRT31 KRT36 LDOC1 MISP MKRN3 MPPED2 OIP5 PFDN5 RINT1 TBC1D21 TEX11 TLE5 TOX2 TRIM23 TRIM27 USHBP1 VPS37C
Entrez ID		26086	158787
HPRD ID		17075	06553
Ensembl ID		ENSG00000160360	ENSG00000158423
Uniprot IDs		A0A087WVF5 A0A0A0MSK4 Q86YR5	Q8N443
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?			Regulation Of Autophagy Establishment Of Localization In Cell Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Organization Identical Protein Binding Supramolecular Fiber Organization
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