GPSM1 and FAM83A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPSM1	FAM83A
Description		G protein signaling modulator 1	family with sequence similarity 83 member A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Cell Cortex Membrane Protein-containing Complex	Cytoplasm Mitochondrion
	Molecular Function	G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding GTPase Regulator Activity	Protein Binding Protein Kinase Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Epidermal Growth Factor Receptor Signaling Pathway Cell Population Proliferation White Fat Cell Differentiation Positive Regulation Of Adipose Tissue Development
Pathways		G alpha (i) signalling events	Signaling by EGFR
Drugs
Diseases
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Myocardial infarction ( 33532862) Offspring birth weight ( 31043758) Type 2 diabetes ( 23945395 32499647 31118516 30718926 30297969 29632382 28869590 26818947) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)	Urinary uromodulin levels ( 24578125)
Interacting Genes		28 interacting genes: BHLHE40 CCDC158 CTDSP1 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 FXR2 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1	23 interacting genes: BHLHE40 CYSRT1 DAZAP2 FOXH1 FOXI1 GCC1 GPSM1 KRT34 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MGAT5B NCK2 PLAGL2 PPP1R16B PRDM14 PSMA3 QARS1 SMYD1 TRIM23 TRIM27 UBASH3A
Entrez ID		26086	84985
HPRD ID		17075	17489
Ensembl ID		ENSG00000160360	ENSG00000147689
Uniprot IDs		A0A087WVF5 A0A0A0MSK4 Q86YR5	Q86UY5
PDB IDs			4URJ
Enriched GO Terms of Interacting Partners?			Intermediate Filament Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
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