HPX and LINC02582

Number of citations of the paper that reports this interaction (PubMedID 31601781)
39

Data Source:
BioGRID (unspecified method)

		HPX	LINC02582
Description		hemopexin	long intergenic non-protein coding RNA 2582
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen Blood Microparticle
	Molecular Function	Protein Binding Heme Transmembrane Transporter Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Intracellular Iron Ion Homeostasis Heme Transport Hemoglobin Metabolic Process Heme Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Response To Type II Interferon Type II Interferon-mediated Signaling Pathway Positive Regulation Of Type II Interferon-mediated Signaling Pathway
Pathways		Scavenging of heme from plasma
Drugs		Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Malaria ( 31844061)
Interacting Genes		4 interacting genes: GLUD1 HSP90AA1 LINC02582 TP63	10 interacting genes: A2M ACTB ALB APOE HBB HPX IGLC6 MAPKAPK3 UMOD USP7
Entrez ID		3263	100505817
HPRD ID		00793
Ensembl ID		ENSG00000110169	ENSG00000261780
Uniprot IDs		P02790 Q9BS19
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamate Dehydrogenase (NAD+) Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, NAD Or NADP As Acceptor Glutamate Dehydrogenase (NADP+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity CTP Binding DATP Binding Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Positive Regulation Of Somatic Stem Cell Population Maintenance Cloacal Septation Ectoderm And Mesoderm Interaction Epidermal Cell Division Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Rho GDP-dissociation Inhibitor Binding Female Genitalia Morphogenesis Negative Regulation Of Mesoderm Development Regulation Of Epidermal Cell Division Prostatic Bud Formation L-leucine Binding Glutamate Biosynthetic Process L-glutamate Catabolic Process Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport Chaperone-mediated Autophagy Sperm Mitochondrial Sheath Positive Regulation Of Cardiac Muscle Contraction Nitric-oxide Synthase Regulator Activity Inclusion Body Assembly Dendritic Growth Cone Sperm Plasma Membrane TPR Domain Binding Telomerase Holoenzyme Complex Assembly Lateral Sprouting From An Epithelium Epithelial Cell Differentiation Involved In Prostate Gland Development Regulation Of Mesoderm Development Negative Regulation Of Keratinocyte Differentiation Morphogenesis Of A Polarized Epithelium Positive Regulation Of Fibroblast Apoptotic Process GTP Binding Positive Regulation Of Cell Size Cardiac Muscle Cell Apoptotic Process Protein Unfolding Positive Regulation Of Striated Muscle Contraction Striated Muscle Cell Apoptotic Process Genitalia Morphogenesis Skin Morphogenesis MDM2/MDM4 Family Protein Binding Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Somatic Stem Cell Population Maintenance	Blood Microparticle Extracellular Space Endocytic Vesicle Lumen Cellular Oxidant Detoxification Extracellular Region Extracellular Exosome Cellular Detoxification Regulation Of Immune Response Regulation Of Innate Immune Response Regulation Of Immune System Process Oxygen Binding Antioxidant Activity One-carbon Compound Transport Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process Platelet Alpha Granule Lumen Regulation Of Humoral Immune Response Platelet Aggregation Tau Protein Binding Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Homotypic Cell-cell Adhesion Negative Regulation Of Phospholipid Efflux Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Regulation Of Nitric Oxide Metabolic Process Intermediate-density Lipoprotein Particle Clearance Renal Absorption Citric Acid Secretion Regulation Of Defense Response Negative Regulation Of Complement Activation, Lectin Pathway Regulation Of Norepinephrine Uptake Enterobactin Binding Exogenous Protein Binding Cellular Response To Calcium Ion Starvation Positive Regulation Of Presynaptic Membrane Organization Chylomicron Remnant Lipid Transport Involved In Lipid Storage Lipoprotein Particle Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle Metanephric Thick Ascending Limb Development Protein Transport Into Plasma Membrane Raft Micturition Regulation Of Protein Localization Intracellular Monoatomic Cation Homeostasis
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