HPX

Name	hemopexin
Structure	No pdb structure
Interactors	4 interactors: GLUD1 HSP90AA1 LINC02582 TP63
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen Blood Microparticle
	Molecular Function	Protein Binding Heme Transmembrane Transporter Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Intracellular Iron Ion Homeostasis Heme Transport Hemoglobin Metabolic Process Heme Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Response To Type II Interferon Type II Interferon-mediated Signaling Pathway Positive Regulation Of Type II Interferon-mediated Signaling Pathway
Pathways	Scavenging of heme from plasma
Drugs	Zinc chloride Zinc sulfate, unspecified form
GWAS	Malaria ( 31844061 )
Entrez ID	3263
HPRD ID	00793
Ensembl ID	ENSG00000110169
Uniprot IDs	P02790 Q9BS19
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Glutamate Dehydrogenase (NAD+) Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, NAD Or NADP As Acceptor Glutamate Dehydrogenase (NADP+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity CTP Binding DATP Binding Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Positive Regulation Of Somatic Stem Cell Population Maintenance Cloacal Septation Ectoderm And Mesoderm Interaction Epidermal Cell Division Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Rho GDP-dissociation Inhibitor Binding Female Genitalia Morphogenesis Negative Regulation Of Mesoderm Development Regulation Of Epidermal Cell Division Prostatic Bud Formation L-leucine Binding Glutamate Biosynthetic Process L-glutamate Catabolic Process Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport Chaperone-mediated Autophagy Sperm Mitochondrial Sheath Positive Regulation Of Cardiac Muscle Contraction Nitric-oxide Synthase Regulator Activity Inclusion Body Assembly Dendritic Growth Cone Sperm Plasma Membrane TPR Domain Binding Telomerase Holoenzyme Complex Assembly Lateral Sprouting From An Epithelium Epithelial Cell Differentiation Involved In Prostate Gland Development Regulation Of Mesoderm Development Negative Regulation Of Keratinocyte Differentiation Morphogenesis Of A Polarized Epithelium Positive Regulation Of Fibroblast Apoptotic Process GTP Binding Positive Regulation Of Cell Size Cardiac Muscle Cell Apoptotic Process Protein Unfolding Positive Regulation Of Striated Muscle Contraction Striated Muscle Cell Apoptotic Process Genitalia Morphogenesis Skin Morphogenesis MDM2/MDM4 Family Protein Binding Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Somatic Stem Cell Population Maintenance