HOXB1 and ZNF835

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOXB1	ZNF835
Description		homeobox B1	zinc finger protein 835
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Domain Specific Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Rhombomere Development Rhombomere 4 Development Rhombomere 5 Development Facial Nerve Structural Organization Facial Nucleus Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Embryonic Skeletal System Morphogenesis	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Body mass index ( 26426971) Colorectal or endometrial cancer ( 26621817) Hemoglobin levels ( 32327693) Keratoconus ( 33649486) Primary tooth development (number of teeth) ( 20195514) Waist circumference ( 28552196)	Vaginal microbiome composition (G. vaginalis) ( 32723796) Western dietary pattern ( 28644415)
Interacting Genes		10 interacting genes: CREBBP EP300 HMGB1 MEIS1 PAX6 PBX1 PKNOX2 RCHY1 SERPINA3 ZNF835	67 interacting genes: BEGAIN BYSL CABP5 CCDC136 CCDC57 CCDC6 CCNDBP1 CDR2L CEP70 CIB3 CLK3 CYSRT1 DEUP1 FSD2 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GUCD1 HAP1 HOOK2 HOXB1 HSF2BP IKBKG IL16 KIFC3 KRT31 KRTAP12-3 KRTAP4-5 LDOC1 MAGOHB MKRN3 MYF5 OSBPL3 POLR1C PRDM14 RINT1 RNF187 RUNDC3A SHCBP1L SHFL SPATA2 STAMBPL1 STX1A TEX12 TLE5 TRAF4 TRIM23 TRIM41 TSPYL2 TULP3 TXK U2AF2 YJU2B ZNF121 ZNF202 ZNF343 ZNF497 ZNF524 ZNF526 ZNF552 ZNF572 ZNF629 ZNF71 ZNF768 ZNF792 ZNF837
Entrez ID		3211	90485
HPRD ID		00855	12521
Ensembl ID		ENSG00000120094	ENSG00000127903
Uniprot IDs		P14653	Q9Y2P0
PDB IDs		1B72
Enriched GO Terms of Interacting Partners?		Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Eye Development DNA Binding Transcription Coregulator Binding Sensory Organ Development DNA-binding Transcription Factor Binding Regulation Of Primary Metabolic Process Damaged DNA Binding Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex P53 Binding Negative Regulation Of Neuron Differentiation Chromatin DNA Binding N-terminal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Metabolic Process Regulation Of Cellular Response To Heat Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Acetyltransferase Activity Pattern Specification Process Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Cell Development Regulation Of RNA Metabolic Process Megakaryocyte Development Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Sequence-specific DNA Binding Anterior/posterior Pattern Specification Chromatin Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Hemopoiesis Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone Acetyltransferase Activity Animal Organ Morphogenesis Regulation Of Neuron Differentiation Protein Acetylation Chromatin Activation Of Innate Immune Response Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process	Identical Protein Binding Protein Binding Zinc Ion Binding Nucleus
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