ZNF835 and RNF187

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF835	RNF187
Description		zinc finger protein 835	ring finger protein 187
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Cell Population Proliferation Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA-templated Transcription Protein Autoubiquitination Protein K48-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS		Vaginal microbiome composition (G. vaginalis) ( 32723796) Western dietary pattern ( 28644415)	Cerebrospinal fluid sTREM-2 levels ( 31708768) Tuberculosis ( 24057671)
Interacting Genes		67 interacting genes: BEGAIN BYSL CABP5 CCDC136 CCDC57 CCDC6 CCNDBP1 CDR2L CEP70 CIB3 CLK3 CYSRT1 DEUP1 FSD2 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GUCD1 HAP1 HOOK2 HOXB1 HSF2BP IKBKG IL16 KIFC3 KRT31 KRTAP12-3 KRTAP4-5 LDOC1 MAGOHB MKRN3 MYF5 OSBPL3 POLR1C PRDM14 RINT1 RNF187 RUNDC3A SHCBP1L SHFL SPATA2 STAMBPL1 STX1A TEX12 TLE5 TRAF4 TRIM23 TRIM41 TSPYL2 TULP3 TXK U2AF2 YJU2B ZNF121 ZNF202 ZNF343 ZNF497 ZNF524 ZNF526 ZNF552 ZNF572 ZNF629 ZNF71 ZNF768 ZNF792 ZNF837	7 interacting genes: JUN PRMT1 TP53 TRIM7 XRN1 ZNF417 ZNF835
Entrez ID		90485	149603
HPRD ID		12521	19493
Ensembl ID		ENSG00000127903	ENSG00000168159
Uniprot IDs		Q9Y2P0	Q5TA31
PDB IDs			7OW2
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Zinc Ion Binding Nucleus	Negative Regulation Of DNA Metabolic Process Viral Process General Transcription Initiation Factor Binding Negative Regulation Of Telomere Maintenance Via Telomerase Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Enzyme Binding GATOR1 Complex Binding Transcription Repressor Complex Positive Regulation Of DNA-templated Transcription Initiation Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Regulation Of Telomere Maintenance Via Telomere Lengthening Cellular Response To Puromycin Cellular Response To Cycloheximide Negative Regulation Of Chromosome Organization DNA Binding Regulation Of DNA-templated Transcription Initiation Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Metabolic Process Regulation Of Fibroblast Proliferation Regulation Of DNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of DNA Metabolic Process Leading Edge Cell Differentiation Transforming Growth Factor Beta Receptor Signaling Pathway Oligodendrocyte Apoptotic Process Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Telomere Maintenance Nucleus Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Anisomycin Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Oxidative Stress-induced Premature Senescence Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Negative Regulation Of Protein Metabolic Process
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