HOXB1

Description		homeobox B1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Domain Specific Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Rhombomere Development Rhombomere 4 Development Rhombomere 5 Development Facial Nerve Structural Organization Facial Nucleus Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Embryonic Skeletal System Morphogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Body mass index ( 26426971) Colorectal or endometrial cancer ( 26621817) Hemoglobin levels ( 32327693) Keratoconus ( 33649486) Primary tooth development (number of teeth) ( 20195514) Waist circumference ( 28552196)
Interacting Genes		10 interacting genes: CREBBP EP300 HMGB1 MEIS1 PAX6 PBX1 PKNOX2 RCHY1 SERPINA3 ZNF835
Entrez ID		3211
HPRD ID		00855
Ensembl ID		ENSG00000120094
Uniprot IDs		P14653
PDB IDs		1B72
Enriched GO Terms of Interacting Partners?		Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Eye Development DNA Binding Transcription Coregulator Binding Sensory Organ Development DNA-binding Transcription Factor Binding Regulation Of Primary Metabolic Process Damaged DNA Binding Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex P53 Binding Negative Regulation Of Neuron Differentiation Chromatin DNA Binding N-terminal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Metabolic Process Regulation Of Cellular Response To Heat Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Acetyltransferase Activity Pattern Specification Process Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Cell Development Regulation Of RNA Metabolic Process Megakaryocyte Development Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Sequence-specific DNA Binding Anterior/posterior Pattern Specification Chromatin Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Hemopoiesis Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone Acetyltransferase Activity Animal Organ Morphogenesis Regulation Of Neuron Differentiation Protein Acetylation Chromatin Activation Of Innate Immune Response Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process
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