ELAVL2 and NR2E3

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ELAVL2	NR2E3
Gene Name		ELAV like neuron-specific RNA binding protein 2	nuclear receptor subfamily 2, group E, member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	Nucleotide Binding MRNA 3'-UTR Binding Protein Binding Poly(A) RNA Binding	Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Visual Perception Phototransduction Negative Regulation Of Cell Proliferation Gene Expression Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Rhodopsin Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS			Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		6 interactors: ELAVL3 ELAVL4 HNRNPAB HOXC9 NR2E3 RBFOX2	27 interactors: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 ZNF232
Entrez ID		1993	10002
HPRD ID		03396	05132
Ensembl ID		ENSG00000107105
Uniprot IDs		Q12926	B6ZGU0 F1D8Q9 Q9Y5X4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rhodopsin Gene Expression System Development Regulation Of Rhodopsin Gene Expression Intracellular Receptor Signaling Pathway Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation Anatomical Structure Morphogenesis Multicellular Organismal Development Negative Regulation Of Transcription, DNA-templated Anatomical Structure Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Organ Development Negative Regulation Of Biosynthetic Process Developmental Process RNA Metabolic Process MRNA Processing Intracellular Estrogen Receptor Signaling Pathway Cell Differentiation Gene Expression Cell Migration In Hindbrain Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Metabolic Process Cell Development RNA Processing Regulation Of Erythrocyte Differentiation Eye Photoreceptor Cell Development Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Photoreceptor Cell Development Regulation Of Nucleic Acid-templated Transcription Eye Photoreceptor Cell Differentiation Regulation Of RNA Biosynthetic Process Cell Morphogenesis Involved In Differentiation Regulation Of RNA Metabolic Process Epithelial To Mesenchymal Transition Nervous System Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process	RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-templated Transcription, Initiation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Steroid Hormone Mediated Signaling Pathway Intracellular Receptor Signaling Pathway Cellular Metabolic Process Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Circadian Regulation Of Gene Expression Circadian Rhythm Rhythmic Process Cellular Response To Steroid Hormone Stimulus Chromatin Modification Positive Regulation Of Metabolic Process Chromatin Organization Regulation Of Receptor Biosynthetic Process Response To Organic Substance
Tagcloud ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived tead1 transfectants transfection transfections tumorigenicity turned usefulness	11a causing compound correlates cytotoxic cytotoxicity eralpha excluding facilitate favorable hct116 hela implying isogenic mediator mutated nci null orphan p53 photoreceptor pleiotropic pnr responsive retain retinal systematic tamoxifen varying
Tagcloud (Difference) ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived tead1 transfectants transfection transfections tumorigenicity turned usefulness	11a causing compound correlates cytotoxic cytotoxicity eralpha excluding facilitate favorable hct116 hela implying isogenic mediator mutated nci null orphan p53 photoreceptor pleiotropic pnr responsive retain retinal systematic tamoxifen varying
Tagcloud (Intersection) ?