DBN1

Description		drebrin 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Gap Junction Cell Cortex Postsynaptic Density Actin Cytoskeleton Membrane Dendrite Growth Cone Cortical Cytoskeleton Actomyosin Cell Projection Neuron Projection Postsynaptic Membrane Anchoring Junction Cell Periphery Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	Actin Binding Protein Binding Profilin Binding Cadherin Binding Protein Sequestering Activity
	Biological Process	In Utero Embryonic Development Actin Filament Organization Nervous System Development Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Cell Differentiation Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Regulation Of Neuronal Synaptic Plasticity Generation Of Neurons Regulation Of Dendrite Development Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Positive Regulation Of Receptor Localization To Synapse
Pathways		RHOD GTPase cycle RHOH GTPase cycle RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		1 novel interacting genes: HNRNPAB
Interacting Genes		29 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 OGT PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 USP7 ZNF598
Entrez ID		1627
HPRD ID		00545
Ensembl ID		ENSG00000113758
Uniprot IDs		Q16643
PDB IDs		5Y1Z 5ZZ9
Enriched GO Terms of Interacting Partners?		Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Organelle Organization Negative Regulation Of Macromolecule Metabolic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomere Lengthening Nucleoplasm Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Negative Regulation Of Biosynthetic Process RNA-templated DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Nucleus Regulation Of DNA Biosynthetic Process Cellular Component Assembly Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Cellular Component Organization Telomere Maintenance DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Chromosome Organization Nuclear Body Regulation Of Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Cytoplasm Cytosol Rhythmic Process Nucleic Acid Metabolic Process Telomere Organization Negative Regulation Of DNA Metabolic Process Telomeric D-loop Disassembly Vagina Development G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
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