CDR2L and TCHP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDR2L	TCHP
Description		cerebellar degeneration related protein 2 like	trichoplein keratin filament binding
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Mitochondrion Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Membrane Desmosome Nuclear Membrane Ciliary Basal Body Keratin Filament Apical Cortex Anchoring Junction Polymeric Cytoskeletal Fiber
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Vesicle Transport Along Microtubule Golgi To Secretory Granule Transport	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Myocardial infarction ( 30226566) Platelet count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		61 interacting genes: ANKRD11 BFSP2 C1orf216 C4orf46 CCDC146 CCDC185 CCDC187 CCHCR1 COX5B DRC12 EHHADH ELOA FAIM FAM161A FAM161B FAM86C1P HDAC4 HSF2BP INO80B KRT31 KRTAP13-4 LENG1 MESD OIP5 PPP1R18 PRPF31 RASAL3 RASD1 REL RINT1 SCNM1 SH2D4A SPMIP6 SPRY1 STX11 SVIP TBRG4 TCEANC TCHP TCP10L TFIP11 TSGA10IP UBE2I USP7 WASHC1 ZBTB42 ZNF19 ZNF250 ZNF35 ZNF417 ZNF572 ZNF629 ZNF648 ZNF655 ZNF669 ZNF688 ZNF80 ZNF835 ZSCAN22 ZSCAN23 ZSCAN26	52 interacting genes: ATPAF2 BCAS2 C21orf91 CBY2 CCDC125 CCDC13 CCDC172 CCDC85B CDR2 CDR2L DMAP1 DYDC1 EIF4ENIF1 HOOK2 ID2 IFFO1 IKZF3 KCTD17 KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT32 KRT34 KRT35 KRT40 KRT5 KRT6A KRT75 KRT8 MIIP MIPOL1 MKRN3 MTUS2 NAB2 NDOR1 NME7 NUP54 PRDM16 PSMB5 RABGEF1 RUSC1 TEX11 TRIM27 TRIM54 USHBP1 VIM WWOX ZIM2
Entrez ID		30850	84260
HPRD ID		11041	14403
Ensembl ID		ENSG00000109089	ENSG00000139437
Uniprot IDs		Q86X02	Q9BT92
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific	Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Structural Molecule Activity Cytoskeleton Organization Cytoskeleton Structural Constituent Of Cytoskeleton Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Cell Differentiation Cellular Developmental Process Organelle Organization Protein Binding Scaffold Protein Binding Epidermis Development Cytosol Keratinization Keratin Filament Binding Cell Periphery Developmental Process Anatomical Structure Morphogenesis Intermediate Filament Cytoskeleton Nuclear Matrix Cornified Envelope Hair Cycle Centrosome Hepatocyte Apoptotic Process
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