HBQ1 and RFESD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		HBQ1	RFESD
Description		hemoglobin subunit theta 1	Rieske Fe-S domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Hemoglobin Complex Haptoglobin-hemoglobin Complex
	Molecular Function	Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Metal Ion Binding	Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Oxygen Transport Erythrocyte Development
Pathways
Drugs
Diseases
GWAS		Hemoglobin ( 32888494) Hemoglobin levels ( 26366553 32327693) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)	Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848)
Interacting Genes		10 interacting genes: AHCYL1 HBA1 HBA2 HBB HBD HBE1 HBG2 HBZ NTAQ1 RFESD	1 interacting genes: HBQ1
Entrez ID		3049	317671
HPRD ID		00791	14164
Ensembl ID		ENSG00000086506	ENSG00000175449
Uniprot IDs		A0A1K0GUV5 P09105	Q8TAC1
PDB IDs
Enriched GO Terms of Interacting Partners?		Haptoglobin-hemoglobin Complex Hemoglobin Complex Oxygen Carrier Activity Carbon Dioxide Transport Oxygen Transport One-carbon Compound Transport Oxygen Binding Erythrocyte Development Myeloid Cell Development Heme Binding Hemoglobin Alpha Binding Hemopoiesis Blood Microparticle Haptoglobin Binding Nitric Oxide Transport Cell Development Endocytic Vesicle Lumen Hydrogen Peroxide Catabolic Process Peroxidase Activity Hydrogen Peroxide Metabolic Process Cellular Oxidant Detoxification Reactive Oxygen Species Metabolic Process Response To Hydrogen Peroxide Cellular Detoxification Iron Ion Binding Response To Reactive Oxygen Species Metal Ion Binding Cellular Developmental Process Protein-N-terminal Glutamine Amidohydrolase Activity G Protein-coupled Receptor Binding Response To Oxidative Stress Adenosylhomocysteinase Activity Protein-N-terminal Asparagine Amidohydrolase Activity S-adenosylmethionine Cycle Cytosol Hemoglobin Binding Inflammatory Response Extracellular Exosome Mitochondrion-endoplasmic Reticulum Membrane Tethering Regulation Of MRNA 3'-end Processing S-adenosylmethionine Metabolic Process Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Developmental Process Erythrocyte Maturation Angiotensin-activated Signaling Pathway One-carbon Metabolic Process Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site 2 Iron, 2 Sulfur Cluster Binding	Hemoglobin Complex Oxygen Transport Haptoglobin-hemoglobin Complex Oxygen Carrier Activity Erythrocyte Development Oxygen Binding Myeloid Cell Development Iron Ion Binding Heme Binding Hemopoiesis
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