HARS and EEF1B2

Number of citations of the paper that reports this interaction (PMID 11829477)
11

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vivo, in vitro)

		HARS	EEF1B2
Gene Name		histidyl-tRNA synthetase	eukaryotic translation elongation factor 1 beta 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	Histidine-tRNA Ligase Activity ATP Binding	Translation Elongation Factor Activity Protein Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Histidyl-tRNA Aminoacylation Gene Expression	Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	Translation Eukaryotic Translation Elongation
Drugs		L-Histidine
Diseases
GWAS
Protein-Protein Interactions		6 interactors: EEF1B2 EEF1G EIF3I RPL5 TARS TNIK	10 interactors: AARS APP CSNK2A1 CSNK2A2 DRD3 EEF1G HARS TIMP1 ULK2 VHL
Entrez ID		3035	1933
HPRD ID		00827	02804
Ensembl ID		ENSG00000170445	ENSG00000114942
Uniprot IDs		B3KWE1 B4DDD8 B4E1C5 P12081	P24534
PDB IDs		1X59 2LW7 4G84 4G85	1B64
Enriched GO Terms of Interacting Partners?		Translation Translational Elongation Cellular Protein Metabolic Process Protein Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Threonyl-tRNA Aminoacylation Translational Initiation Biosynthetic Process Activation Of JNKK Activity Ribonucleoprotein Complex Biogenesis Protein Localization To Membrane Microvillus Assembly Microvillus Organization	Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Neuromuscular Process Response To External Stimulus Regulation Of Cell Cycle Process Cell Morphogenesis Cellular Protein Metabolic Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Regulation Of Mitotic Cell Cycle Phase Transition Neuron Projection Morphogenesis Regulation Of Cell Cycle Phase Transition Regulation Of Proteolysis Nervous System Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Cell Division Negative Regulation Of Endopeptidase Activity Cell Morphogenesis Involved In Differentiation Negative Regulation Of Peptidase Activity Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Negative Regulation Of Catalytic Activity Regulation Of Mitotic Metaphase/anaphase Transition Generation Of Neurons Developmental Process Negative Regulation Of Cellular Protein Metabolic Process Protein Metabolic Process Neuron Projection Development Cell Projection Morphogenesis Negative Regulation Of Cell Development Visual Learning Cell Part Morphogenesis Neurogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Visual Behavior Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Apoptotic Process Platelet Degranulation
Tagcloud ?		ascertain botulinum cgi clinician compulsive dysphonia ghq hamilton hdrs impression obsessive pathologist psychometrics psychoticism ql rated rating reevaluated sds somatization somatoform spasmodic speech subscales toxin unilaterally vocal voice zung	aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox
Tagcloud (Difference) ?		ascertain botulinum cgi clinician compulsive dysphonia ghq hamilton hdrs impression obsessive pathologist psychometrics psychoticism ql rated rating reevaluated sds somatization somatoform spasmodic speech subscales toxin unilaterally vocal voice zung	aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox
Tagcloud (Intersection) ?