HAGH and BST2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HAGH	BST2
Gene Name		hydroxyacylglutathione hydrolase	bone marrow stromal cell antigen 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Extracellular Vesicular Exosome	Cytoplasm Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Anchored Component Of Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Zinc Ion Binding	Signal Transducer Activity Protein Binding Metalloendopeptidase Inhibitor Activity Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	Glutathione Biosynthetic Process	Negative Regulation Of Plasmacytoid Dendritic Cell Cytokine Production Humoral Immune Response Cell-cell Signaling Multicellular Organismal Development Cell Proliferation Response To Virus Negative Regulation Of Endopeptidase Activity Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta B Cell Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material
Pathways			Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs		Glutathione S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP BST2 MYOC TERF2IP	2 interactors: HAGH HARS2
Entrez ID		3029	684
HPRD ID		00731	02759
Ensembl ID		ENSG00000063854	ENSG00000130303
Uniprot IDs		E7EN93 Q16775	Q10589
PDB IDs		1QH3 1QH5 2F50	2LK9 2X7A 2XG7 3MQ7 3MQ9 3MQB 3MQC 3NWH
Enriched GO Terms of Interacting Partners?		Neuron Maturation Positive Regulation Of Intracellular Signal Transduction ERBB2-ERBB3 Signaling Pathway Negative Regulation Of Plasmacytoid Dendritic Cell Cytokine Production Skeletal Muscle Hypertrophy Negative Regulation Of DNA Recombination At Telomere Regulation Of Signal Transduction Regulation Of Organelle Organization Cell Maturation Regulation Of Signaling ERBB2 Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Dendritic Cell Cytokine Production Synaptic Growth At Neuromuscular Junction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Collateral Sprouting In Absence Of Injury Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Signal Transduction Negative Regulation Of Endopeptidase Activity Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Negative Regulation Of Peptidase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Non-canonical Wnt Signaling Pathway Via JNK Cascade Protein Localization To Chromosome, Telomeric Region Axon Choice Point Recognition Non-canonical Wnt Signaling Pathway Via MAPK Cascade Clustering Of Voltage-gated Sodium Channels Negative Regulation Of Proteolysis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Processing Neuron Remodeling Skeletal Muscle Adaptation Regulation Of Endopeptidase Activity Regulation Of Intracellular Signal Transduction Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Actin Filament-based Process Regulation Of Peptidase Activity Negative Regulation Of Stress Fiber Assembly Neuronal Ion Channel Clustering Regulation Of Cellular Component Organization Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cellular Metabolic Process	Histidyl-tRNA Aminoacylation D-amino Acid Catabolic Process Regulation Of Translational Fidelity Glutathione Biosynthetic Process Peptide Biosynthetic Process Glutathione Metabolic Process TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Cellular Amino Acid Catabolic Process Peptide Metabolic Process
Tagcloud ?		2alpha aging copy e2f4 element enhancer fungi glo1 glo2 glycation glyoxalase hotspot hydrolase hydroxyacylglutathione inducers ire isoform malaria markedly mathematical methylglyoxal modelling mre multidrug pathogenic permeant pharmacological predicts sustain	aberrantly antiviral arisen cd317 chimpanzees defective determinants divergence endocytic endocytosis hominids motifs nfkappab perfectly physically positioned proinflammatory recognize restriction retention sensor tail tak1 tetherin tethering traf6 virion virions vpu
Tagcloud (Difference) ?		2alpha aging copy e2f4 element enhancer fungi glo1 glo2 glycation glyoxalase hotspot hydrolase hydroxyacylglutathione inducers ire isoform malaria markedly mathematical methylglyoxal modelling mre multidrug pathogenic permeant pharmacological predicts sustain	aberrantly antiviral arisen cd317 chimpanzees defective determinants divergence endocytic endocytosis hominids motifs nfkappab perfectly physically positioned proinflammatory recognize restriction retention sensor tail tak1 tetherin tethering traf6 virion virions vpu
Tagcloud (Intersection) ?