BST2

Name	bone marrow stromal cell antigen 2
Structure
Novel Interactors	2 novel interactors: GATAD2A WT1
Interactors	3 interactors: CD81 HAGH HARS2
GO Annotations	Cellular Component	Cytoplasm Endosome Late Endosome Multivesicular Body Golgi Apparatus Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Azurophil Granule Membrane Membrane Raft Extracellular Exosome Side Of Membrane
	Molecular Function	RNA Binding Protein Binding Metalloendopeptidase Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Immune System Process Negative Regulation Of Plasmacytoid Dendritic Cell Cytokine Production Response To Virus Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Response To Type II Interferon Response To Interferon-alpha Response To Interferon-beta B Cell Activation Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Positive Regulation Of Leukocyte Proliferation Negative Regulation Of Intracellular Transport Of Viral Material
Pathways	Neutrophil degranulation Interferon alpha/beta signaling SARS-CoV-1 activates/modulates innate immune responses
GWAS	No GWAS studies recorded
Entrez ID	684
HPRD ID	02759
Ensembl ID	ENSG00000130303
Uniprot IDs	A0A024R7H5 Q10589
PDB IDs	2LK9 2X7A 2XG7 3MQ7 3MQ9 3MQB 3MQC 3NWH 4P6Z 6CM9 6CRI 6D83 6D84 6DFF 7Q9A
GO Terms Enriched among Interactors ?	Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Myoblast Fusion Involved In Skeletal Muscle Regeneration Hydroxyacylglutathione Hydrolase Activity Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Negative Regulation Of Female Gonad Development Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Negative Regulation Of Glomerular Mesangial Cell Proliferation Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Histidine-tRNA Ligase Activity Histidyl-tRNA Aminoacylation Methylglyoxal Catabolic Process To Lactate Cellular Detoxification Of Methylglyoxal Hemi-methylated DNA-binding Metanephric S-shaped Body Morphogenesis MHC Class II Protein Binding Humoral Immune Response Mediated By Circulating Immunoglobulin Osteoclast Fusion Methylglyoxal Metabolic Process Negative Regulation Of Cell Proliferation Involved In Kidney Development Thorax And Anterior Abdomen Determination S-shaped Body Morphogenesis Double-stranded Methylated DNA Binding Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Protein Catabolic Process In The Vacuole Diaphragm Development Regulation Of Female Gonad Development Positive Regulation Of Male Gonad Development Cardiac Muscle Cell Fate Commitment Metanephric Mesenchyme Development Positive Regulation Of T-helper 2 Cell Cytokine Production Tetraspanin-enriched Microdomain Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Transferrin Receptor Binding Immunological Synapse Formation Positive Regulation Of Receptor Clustering Positive Regulation Of Inflammatory Response To Antigenic Stimulus Glutathione Biosynthetic Process Aldehyde Catabolic Process Cellular Detoxification Of Aldehyde Metanephric Epithelium Development Muscle Cell Fate Commitment Nephron Tubule Morphogenesis Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation