HAGH

Gene Name		hydroxyacylglutathione hydrolase
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Zinc Ion Binding
	Biological Process	Glutathione Biosynthetic Process
Pathways
Drugs		Glutathione S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP BST2 MYOC TERF2IP
Entrez ID		3029
HPRD ID		00731
Ensembl ID		ENSG00000063854
Uniprot IDs		E7EN93 Q16775
PDB IDs		1QH3 1QH5 2F50
Enriched GO Terms of Interacting Partners?		Neuron Maturation Positive Regulation Of Intracellular Signal Transduction ERBB2-ERBB3 Signaling Pathway Negative Regulation Of Plasmacytoid Dendritic Cell Cytokine Production Skeletal Muscle Hypertrophy Negative Regulation Of DNA Recombination At Telomere Regulation Of Signal Transduction Regulation Of Organelle Organization Cell Maturation Regulation Of Signaling ERBB2 Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Dendritic Cell Cytokine Production Synaptic Growth At Neuromuscular Junction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Collateral Sprouting In Absence Of Injury Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Signal Transduction Negative Regulation Of Endopeptidase Activity Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Negative Regulation Of Peptidase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Non-canonical Wnt Signaling Pathway Via JNK Cascade Protein Localization To Chromosome, Telomeric Region Axon Choice Point Recognition Non-canonical Wnt Signaling Pathway Via MAPK Cascade Clustering Of Voltage-gated Sodium Channels Negative Regulation Of Proteolysis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Processing Neuron Remodeling Skeletal Muscle Adaptation Regulation Of Endopeptidase Activity Regulation Of Intracellular Signal Transduction Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Actin Filament-based Process Regulation Of Peptidase Activity Negative Regulation Of Stress Fiber Assembly Neuronal Ion Channel Clustering Regulation Of Cellular Component Organization Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		2alpha aging copy e2f4 element enhancer fungi glo1 glo2 glycation glyoxalase hotspot hydrolase hydroxyacylglutathione inducers ire isoform malaria markedly mathematical methylglyoxal modelling mre multidrug pathogenic permeant pharmacological predicts sustain