HAGH

Description		hydroxyacylglutathione hydrolase
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Glutathione Metabolic Process Glutathione Biosynthetic Process Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione
Pathways
Drugs		Glutathione S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: TIMM10
Interacting Genes		6 interacting genes: APOBEC3A APP BST2 MYOC SHANK3 TERF2IP
Entrez ID		3029
HPRD ID		00731
Ensembl ID		ENSG00000063854
Uniprot IDs		H3BPQ4 Q16775
PDB IDs		1QH3 1QH5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Cell Communication Amylin Binding Positive Regulation Of Signaling Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Signal Transduction Frizzled Binding Modulation Of Excitatory Postsynaptic Potential Regulation Of Viral Genome Replication Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Negative Regulation Of Viral Process Negative Regulation Of Viral Genome Replication Negative Regulation Of Plasmacytoid Dendritic Cell Cytokine Production Negative Regulation Of Actin Filament Bundle Assembly Skeletal Muscle Hypertrophy Mitochondrial Intermembrane Space Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Positive Regulation Of Cellular Component Organization Associative Learning Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Membrane Potential Positive Regulation Of JNK Cascade Neuron Projection Development Positive Regulation Of Intracellular Signal Transduction Lipoprotein Particle Mitochondrial Inner Membrane Positive Regulation Of Protein Import Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Dendritic Cell Cytokine Production Regulation Of Organelle Organization Negative Regulation Of DNA Recombination At Telomere Guanylate Kinase-associated Protein Clustering Regulation Of Viral Life Cycle Regulation Of Cellular Component Organization PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import
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