H2AZ1 and MAGEC1

Number of citations of the paper that reports this interaction (PubMedID 17137291)
0

Data Source:
HPRD (two hybrid)

		H2AZ1	MAGEC1
Description		H2A.Z variant histone 1	MAGE family member C1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleosome Euchromatin Heterochromatin Barr Body Nucleus Chromosome Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding Structural Constituent Of Chromatin Chromatin DNA Binding Nucleosomal DNA Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	Chromatin Organization Heterochromatin Formation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estradiol Stimulus	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS			High-grade serous ovarian cancer ( 31469419) Hodgkin's lymphoma ( 34216518)
Interacting Genes		8 interacting genes: FH INCENP MAGEC1 NCAPH PIAS1 RNF168 RNF169 USP16	8 interacting genes: ATP5MG CTAG1B ECHDC2 GTF2F1 H2AZ1 MRPL19 ROCK2 RUSC2
Entrez ID		3015	9947
HPRD ID		00823	02201
Ensembl ID		ENSG00000164032	ENSG00000155495
Uniprot IDs		P0C0S5	O60732
PDB IDs		1F66 3WA9 4CAY 4NFT 5B31 5B32 5B33 5CHL 5FUG 5Z30 6JOU 6KO2 7YRD 7YRG 8JHF 8T9F 8THU 9C62
Enriched GO Terms of Interacting Partners?		DNA Damage Response Site Of Double-strand Break Histone Binding DNA Repair K63-linked Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Chromosome Separation Positive Regulation Of Chromosome Segregation Nucleosome Binding Chromosome Regulation Of DNA Repair Double-strand Break Repair DNA Recombination DNA Metabolic Process Cellular Response To Stress Fumarate Metabolic Process Fumarate Hydratase Activity Nucleus Meiotic Spindle Midzone Post-translational Protein Modification Positive Regulation Of Ribosome Biogenesis Double-strand Break Repair Via Nonhomologous End Joining Histone H2AK15 Ubiquitin Ligase Activity Regulation Of Chromosome Separation Nuclear Division Regulation Of Cell Cycle Meiotic Spindle Midzone Assembly Cell Division Female Meiosis Chromosome Separation Ubiquitin Binding Regulation Of DNA Metabolic Process Histone Ubiquitin Ligase Activity Regulation Of Cellular Response To Stress Positive Regulation Of DNA Repair Regulation Of Chromosome Segregation Chromosome Segregation Mitotic Cell Cycle Recombinational Repair Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Translational Elongation Meiotic Chromosome Separation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Double-strand Break Repair Regulation Of Arginine Metabolic Process Female Meiosis Chromosome Segregation Nucleoplasm Chromosome Passenger Complex Regulation Of Ribosome Biogenesis Mitotic Nuclear Division Histone H2A Deubiquitinase Activity Meiotic Chromosome Condensation
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