H2AFZ

Gene Name		H2A histone family, member Z
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Gene Ontology Annotations	Cellular Component	Nucleosome Barr Body Nucleus Nuclear Euchromatin Nuclear Heterochromatin Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Estradiol Stimulus
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic RMTs methylate histone arginines Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: INCENP MAGEC1 NCAPH
Entrez ID		3015
HPRD ID		00823
Ensembl ID		ENSG00000164032
Uniprot IDs		P0C0S5
PDB IDs		1F66
Enriched GO Terms of Interacting Partners?		Chromosome Segregation Mitotic Nuclear Division Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Process Mitotic Chromosome Condensation Cell Cycle Chromosome Condensation Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Cytokinesis DNA Packaging Organelle Organization DNA Conformation Change
Tagcloud ?		adrbk1 bisulfite ccne2 chimpanzee crabp1 cxcl6 derive dsc2 ega embryos endangered gapdh glut1 h3k27 h4k5 interspecies iscnt klf4 lin28 nanog oct4 ooplasm ptger4 remodel scnt soon stella usf2 utp