FCAR and OSCAR

Number of citations of the paper that reports this interaction (PubMedID 15085135)
0

Data Source:
HPRD (in vitro)

		FCAR	OSCAR
Description		Fc alpha receptor	osteoclast associated Ig-like receptor
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Extracellular Region Plasma Membrane Membrane Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	IgA Receptor Activity IgA Binding	Collagen Receptor Activity
	Biological Process	Neutrophil Mediated Immunity Immune Response-regulating Signaling Pathway Immune Response Positive Regulation Of Neutrophil Apoptotic Process Cellular Response To Interferon-alpha Fc Receptor Signaling Pathway Neutrophil Activation Cellular Response To Lipopolysaccharide Cellular Response To Type II Interferon Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus	Immune Response-regulating Signaling Pathway Osteoclast Differentiation Collagen-activated Signaling Pathway
Pathways		Neutrophil degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Ulcerative colitis ( 28067908)	Blood protein levels ( 30072576) Response to taxane treatment (docetaxel) ( 23006423)
Interacting Genes		6 interacting genes: CD79A FCGR1A LYN OSCAR PILRA PPP2CA	1 interacting genes: FCAR
Entrez ID		2204	126014
HPRD ID		00914	06035
Ensembl ID		ENSG00000186431	ENSG00000170909
Uniprot IDs		A0A1P8A760 P24071	A0A087WV17 A0A087X1R2 A0A0A0MR14 A0A0A0MRF2 Q8IYS5
PDB IDs		1OVZ 1OW0 1UCT 8SKU	5CJ8 5CJB 5EIQ 5EIV
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Signaling Pathway Adaptive Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Membrane Raft B Cell Proliferation Fc-gamma Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Immune Response Fc Receptor Signaling Pathway Leukocyte Differentiation Lymphocyte Homeostasis Signal Transduction Plasma Membrane High-affinity IgG Receptor Activity Leukocyte Homeostasis RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune Response IgM B Cell Receptor Complex Lymphocyte Proliferation Leukocyte Proliferation Mononuclear Cell Proliferation Immune System Process Regulation Of Immune System Process B Cell Receptor Complex Positive Regulation Of Type IIa Hypersensitivity Positive Regulation Of Type III Hypersensitivity Platelet Degranulation Histamine Secretion By Mast Cell Negative Regulation Of Mast Cell Proliferation Myeloid Leukocyte Differentiation Fc Receptor Mediated Inhibitory Signaling Pathway Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Postsynaptic Specialization, Intracellular Component Positive Regulation Of Mast Cell Proliferation Integrin Alpha2-beta1 Complex Tolerance Induction To Self Antigen Positive Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Phosphate Metabolic Process Positive Regulation Of Dendritic Cell Apoptotic Process Homeostasis Of Number Of Cells Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Collagen Receptor Activity B Cell Activation IgG Receptor Activity Regulation Of Oligodendrocyte Progenitor Proliferation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway	IgA Receptor Activity IgA Binding Positive Regulation Of Neutrophil Apoptotic Process Regulation Of Neutrophil Apoptotic Process Positive Regulation Of Myeloid Cell Apoptotic Process Cellular Response To Interferon-alpha Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Cellular Response To Interleukin-6 Response To Interleukin-6 Response To Interferon-alpha Neutrophil Mediated Immunity Positive Regulation Of Leukocyte Apoptotic Process Regulation Of Myeloid Cell Apoptotic Process Neutrophil Activation Ficolin-1-rich Granule Membrane Fc Receptor Signaling Pathway Tertiary Granule Membrane Cellular Response To Type II Interferon Specific Granule Membrane Response To Type II Interferon Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor Myeloid Leukocyte Activation Leukocyte Mediated Immunity Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Immune Effector Process
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