FCAR and CD79A

Number of citations of the paper that reports this interaction (PMID 10438530)
24

Data Source:
HPRD (in vivo)

		FCAR	CD79A
Gene Name		Fc fragment of IgA, receptor for	CD79a molecule, immunoglobulin-associated alpha
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft
	Molecular Function	IgA Binding	Transmembrane Signaling Receptor Activity
	Biological Process	Immune Response	B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways			Signaling by the B Cell Receptor (BCR) Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CD79A FCGR1A LYN OSCAR PILRA PPP2CA	17 interactors: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM IGJ LCK LYN PIGR PTPN6 SYK
Entrez ID		2204	973
HPRD ID		00914	00203
Ensembl ID		ENSG00000186431	ENSG00000105369
Uniprot IDs		P24071	P11912
PDB IDs		1OVZ 1OW0 1UCT	1CV9
Enriched GO Terms of Interacting Partners?		Immune Response-activating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of MAP Kinase Activity Regulation Of JAK-STAT Cascade Positive Regulation Of Immune Response Positive Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Mast Cell Proliferation Negative Regulation Of Protein Serine/threonine Kinase Activity Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of MAPK Cascade Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Signal Transduction Tolerance Induction To Self Antigen Fc Receptor Mediated Inhibitory Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Regulation Of Peptidyl-tyrosine Phosphorylation Signaling Negative Regulation Of Protein Kinase Activity Cell Communication Negative Regulation Of Kinase Activity Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Immune Response-inhibiting Signal Transduction Phagocytosis Fc Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of MAP Kinase Activity Regulation Of Immune System Process Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Tolerance Induction Positive Regulation Of Mast Cell Proliferation Negative Regulation Of Transferase Activity Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Protein Phosphorylation Cellular Response To Stimulus Leukocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Mitotic Nuclear Envelope Reassembly Protein Heterotrimerization Histamine Secretion By Mast Cell Nuclear Envelope Reassembly	B Cell Receptor Signaling Pathway Immune System Process Antigen Receptor-mediated Signaling Pathway Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Immune System Process Regulation Of Immune System Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Regulation Of Immune Response T Cell Costimulation Enzyme Linked Receptor Protein Signaling Pathway Defense Response Positive Regulation Of Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Response To Stimulus Hemopoiesis Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Cell Activation Regulation Of Lymphocyte Activation Platelet Activation Immune System Development Protein Autophosphorylation Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Regulation Of Cell Activation Leukocyte Activation Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Response To Stress Cellular Response To Peptide Homotypic Cell-cell Adhesion Regulation Of Cell Proliferation Regulation Of Cell Adhesion Leukocyte Differentiation Regulation Of Cellular Localization Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Tagcloud ?		anca antineutrophil assembled cd11b confocal degranulation engagement extracellcular fcgr3b fcr fcrs genetics granulomatosis haplotype iga igg illumina mucosal multicenter na1 na2 neutrophil polyangiitis pyrosequencing tagging taqman unappreciated vasculitis wegener	abdomen axillae bence cd138 cd20 cd56 dermis disappearing emp enlarged extramedullar fig immunohistological inguinal jones microglobulin monotypic painless pcp pcps plasmacytoid plasmacytoma pointed reappeared runs subcutis temporarily vincristine
Tagcloud (Difference) ?		anca antineutrophil assembled cd11b confocal degranulation engagement extracellcular fcgr3b fcr fcrs genetics granulomatosis haplotype iga igg illumina mucosal multicenter na1 na2 neutrophil polyangiitis pyrosequencing tagging taqman unappreciated vasculitis wegener	abdomen axillae bence cd138 cd20 cd56 dermis disappearing emp enlarged extramedullar fig immunohistological inguinal jones microglobulin monotypic painless pcp pcps plasmacytoid plasmacytoma pointed reappeared runs subcutis temporarily vincristine
Tagcloud (Intersection) ?