SCHIP1 and TMSB4X

Number of citations of the paper that reports this interaction (PubMedID 20195357)
57

Data Source:
BioGRID (pull down)

		SCHIP1	TMSB4X
Description		schwannomin interacting protein 1	thymosin beta 4 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Junction	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Actin Binding Actin Monomer Binding Actin Monomer Sequestering Activity Protein Binding Enzyme Binding Protein Sequestering Activity
	Biological Process	Positive Regulation Of Hippo Signaling	Actin Filament Organization Regulation Of Cell Migration Negative Regulation Of Actin Filament Polymerization Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Inflammatory Response Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Celiac disease ( 18311140 22057235 25920553) Congenital heart disease (maternal effect) ( 28468790) Conotruncal heart defects (maternal effects) ( 28468790) Eosinophil count ( 32888494) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin saturation) ( 28334935) Limited cutaneous systemic scleroderma ( 24387989) Major depressive disorder ( 23377640) Myeloproliferative neoplasms ( 33057200) Primary biliary cholangitis ( 26394269) Quantitative traits ( 19197348) Self-reported childhood asthma in adult smokers ( 30373671) Systemic sclerosis ( 24387989) Upper eyelid morphology ( 29921221)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		11 interacting genes: FOS HTR6 NF2 PRPF18 PSMD4 PTMS SCOC SMARCD1 SYCE1L TMSB4X ZC3H13	38 interacting genes: ACTA1 ACTA2 ACTB ACTG1 AKAP8L ALAS1 ANXA7 APLP1 CDKN1A COG6 FAM118B FHL3 GOLGA6L9 GRB7 HSF2BP IGSF21 ILK KRT13 KRT15 KRT31 KRT34 KRT36 KRT40 KRTAP8-1 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6 UHMK1
Entrez ID		29970	7114
HPRD ID		15302	02153
Ensembl ID		ENSG00000151967	ENSG00000205542
Uniprot IDs		A0A8I5KTZ3 C9JWG6 P0DPB3	A2VCK8 P62328 Q0P5T0
PDB IDs			3TU5 4PL7 4PL8
Enriched GO Terms of Interacting Partners?			Morphogenesis Of An Epithelium Structural Constituent Of Skin Epidermis Tissue Morphogenesis Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Epithelial Cell Differentiation Structural Constituent Of Cytoskeleton Cytosol Structural Molecule Activity Focal Adhesion Supramolecular Fiber Organization Regulation Of Transepithelial Transport Stress Fiber Cytoskeleton Organization Mesenchyme Migration Dense Body Protein Kinase Binding Identical Protein Binding Developmental Process Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Platelet Aggregation Organelle Organization Anatomical Structure Morphogenesis Epidermis Development Actin Cytoskeleton Homotypic Cell-cell Adhesion Postsynaptic Actin Cytoskeleton Organization Cellular Response To Catecholamine Stimulus Lamellipodium Protein Localization To Cell-cell Junction Calyx Of Held Response To Catecholamine Actin Filament Postsynaptic Cytoskeleton Organization Protein Binding Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Hepatic Stellate Cell Contraction Apical Junction Complex NuA4 Histone Acetyltransferase Complex Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Synaptic Vesicle Recycling Basal Body Patch Alpha-2B Adrenergic Receptor Binding Peptide Dopaminyltransferase Activity
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