GYPC and SHISAL1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		GYPC	SHISAL1
Name		glycophorin C (Gerbich blood group)	shisa like 1
Structure			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cortical Cytoskeleton	Membrane
GO Annotations	Molecular Function	Protein Binding	Protein Binding
Pathways		Cell surface interactions at the vascular wall	None
GWAS		Atrial fibrillation ( 29892015 30061737 ) Diastolic blood pressure ( 30224653 ) Hemoglobin levels ( 32327693 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Initial pursuit acceleration ( 29064472 ) Intelligence ( 22449649 ) Metabolite levels ( 23823483 ) Pelvic organ prolapse (moderate/severe) ( 26545240 ) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271 ) Reticulocyte count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 ) Systolic blood pressure ( 31217584 ) Tea consumption ( 31046077 )	No GWAS studies recorded
Interacting Genes		13 interacting genes: ABHD16A AQP6 EPB41 GPR42 MPP1 PDIA3 PLPPR2 RHBDD1 SHISAL1 SLC10A6 TMEM14B TMEM88 TSPAN15	28 interacting genes: ALG10 ALG10B ARLN ASPH CATSPERH CYB561A3 GIMAP5 GJB2 GPR151 GPR25 GYPC LPAR3 MFF MFSD6 PLPP6 PMP22 SCAMP5 SLC16A13 SLC35B2 SLC38A7 SLC39A7 SLC41A2 SLC52A1 SLC61A1 TMEM128 TMEM140 TMEM42 ZFPL1
Entrez ID		2995	85352
HPRD ID		00193	19361
Ensembl ID		ENSG00000136732	ENSG00000138944
Uniprot IDs		P04921	Q3SXP7
PDB IDs		2EJY	Not available
GO Terms Enriched among Interactors		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Membrane Cortical Cytoskeleton Tapasin-ERp57 Complex Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport	Membrane Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity Bleb Assembly Transmembrane Transport Dolichol-linked Oligosaccharide Biosynthetic Process