GYPC and PLPPR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GYPC	PLPPR2
Description		glycophorin C (Gerbich blood group)	phospholipid phosphatase related 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cortical Cytoskeleton	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Phosphatidate Phosphatase Activity
	Biological Process		Phospholipid Metabolic Process Signal Transduction Phospholipid Dephosphorylation
Pathways		Cell surface interactions at the vascular wall	Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015 30061737) Diastolic blood pressure ( 30224653) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Initial pursuit acceleration ( 29064472) Intelligence ( 22449649) Metabolite levels ( 23823483) Pelvic organ prolapse (moderate/severe) ( 26545240) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 31217584) Tea consumption ( 31046077)
Interacting Genes		13 interacting genes: ABHD16A AQP6 EPB41 GPR42 MPP1 PDIA3 PLPPR2 RHBDD1 SHISAL1 SLC10A6 TMEM14B TMEM88 TSPAN15	21 interacting genes: ARL13B CD79A CIAO2A CISD2 CLDN5 CREB3L1 GYPC KIR2DL3 LYPD5 MARCHF2 SCN3B SIGLEC12 SLC19A3 SMAGP SSMEM1 STX12 TMED9 TMEM237 TMIE UBE2J1 VSIR
Entrez ID		2995	64748
HPRD ID		00193	17442
Ensembl ID		ENSG00000136732	ENSG00000105520
Uniprot IDs		P04921	A0A8I5KWF3 Q96GM1
PDB IDs		2EJY
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Membrane Cortical Cytoskeleton Tapasin-ERp57 Complex Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport	Membrane
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?