GMPPB and GMPPA

Number of citations of the paper that reports this interaction (PMID 22863883)
15

Data Source:
BioGRID (two hybrid, biochemical)
HPRD (in vivo)

		GMPPB	GMPPA
Gene Name		GDP-mannose pyrophosphorylase B	GDP-mannose pyrophosphorylase A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Extracellular Vesicular Exosome	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Mannose-1-phosphate Guanylyltransferase Activity GTP Binding	Nucleotidyltransferase Activity
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process GDP-mannose Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process	Dolichol-linked Oligosaccharide Biosynthetic Process GDP-mannose Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Synthesis of GDP-mannose Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins	Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Synthesis of GDP-mannose Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS		Ulcerative colitis ( 21297633)
Protein-Protein Interactions		2 interactors: GMPPA TXNDC5	5 interactors: BTC CDR2 CRP GMPPB LSM8
Entrez ID		29925	29926
HPRD ID		13589	13588
Ensembl ID		ENSG00000173540	ENSG00000144591
Uniprot IDs		Q9Y5P6	Q96IJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		fkrp lgmd1 lgmd1c lgmd1h lgmd2 lgmd2d lgmd2e lgmd2f lgmd2g lgmd2h lgmd2i lgmd2j lgmd2k lgmd2l lgmd2m lgmd2n lgmd2o lgmd2p lgmd2q lgmd2r lgmd2s lgmd2t lgmd2u lgmd2v lgmd2w pinch2 pomtng1 thity trappc11
Tagcloud (Difference) ?		fkrp lgmd1 lgmd1c lgmd1h lgmd2 lgmd2d lgmd2e lgmd2f lgmd2g lgmd2h lgmd2i lgmd2j lgmd2k lgmd2l lgmd2m lgmd2n lgmd2o lgmd2p lgmd2q lgmd2r lgmd2s lgmd2t lgmd2u lgmd2v lgmd2w pinch2 pomtng1 thity trappc11
Tagcloud (Intersection) ?