GMPPB

Description		GDP-mannose pyrophosphorylase B
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GO Annotations	Cellular Component	Cytoplasm Cytosol GDP-mannose Pyrophosphorylase Complex
	Molecular Function	Nucleotide Binding Mannose-1-phosphate Guanylyltransferase (GTP) Activity Protein Binding GTP Binding Transferase Activity Nucleotidyltransferase Activity Metal Ion Binding
	Biological Process	Protein Glycosylation GDP-mannose Biosynthetic Process GDP-mannose Metabolic Process GDP-mannose Biosynthetic Process From Mannose
Pathways		Synthesis of GDP-mannose
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Multisite chronic pain ( 31194737) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Resting heart rate ( 27798624) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 21297633)
Novel Interacting Genes		1 novel interacting genes: SETD2
Interacting Genes		5 interacting genes: DPPA4 GLYCTK GMPPA POLR1C TXNDC5
Entrez ID		29925
HPRD ID		13589
Ensembl ID		ENSG00000173540
Uniprot IDs		Q9Y5P6
PDB IDs		7D72 7D73 7D74
Enriched GO Terms of Interacting Partners?		Molecular Sensor Activity GDP-mannose Pyrophosphorylase Complex Mannose-1-phosphate Guanylyltransferase (GTP) Activity Fructose Catabolic Process Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Glycerate Kinase Activity
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