OLA1 and TUBG1

Number of citations of the paper that reports this interaction (PMID 24289923)
0

Data Source:
BioGRID (pull down)

		OLA1	TUBG1
Gene Name		Obg-like ATPase 1	tubulin, gamma 1
Image
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Centrosome Membrane Extracellular Vesicular Exosome	Pericentriolar Material Condensed Nuclear Chromosome Gamma-tubulin Complex Cytoplasm Centrosome Centriole Polar Microtubule Cytosol Cytoplasmic Microtubule Cell Leading Edge Nonmotile Primary Cilium Ciliary Basal Body Apical Part Of Cell Recycling Endosome
	Molecular Function	Protein Binding ATP Binding GTP Binding ATPase Activity Ribosome Binding Ribosomal Large Subunit Binding Metal Ion Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Organelle Organization Microtubule Nucleation Cytoplasmic Microtubule Organization
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ASCC2 BARD1 BRCA1 HMGA1 PRMT5 TUBG1	24 interactors: BRCA1 CENPJ CNTN2 IKBKG KRT18 KRT19 MARK4 NAPG NDE1 OLA1 PCNT PIK3R1 PLK1 PXN RACGAP1 RASSF1 RNF19A RPGR SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4
Entrez ID		29789	7283
HPRD ID		15194	01853
Ensembl ID		ENSG00000138430	ENSG00000131462
Uniprot IDs		Q9NTK5	P23258
PDB IDs		2OHF	1Z5V 1Z5W 3CB2
Enriched GO Terms of Interacting Partners?		Protein K6-linked Ubiquitination Negative Regulation Of Gene Expression Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation DNA Repair Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Negative Regulation Of MRNA 3'-end Processing Oncogene-induced Cell Senescence Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Senescence-associated Heterochromatin Focus Assembly Protein Polyubiquitination Cellular Response To DNA Damage Stimulus Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Senescence Regulation Of Cell Cycle Regulation Of Gene Expression, Epigenetic Cellular Response To Indole-3-methanol Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Centriole Replication Cell Cycle Process DNA Metabolic Process Negative Regulation Of Protein Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Chromatin Silencing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Establishment Of Integrated Proviral Latency Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription DNA Replication Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Cellular Nitrogen Compound Metabolic Process Establishment Of Viral Latency Regulation Of Centriole Replication Histone H4-R3 Methylation Heterochromatin Assembly Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process Meiotic Spindle Organization	Microtubule-based Process Microtubule Cytoskeleton Organization Cytoskeleton Organization G2/M Transition Of Mitotic Cell Cycle Protein Polymerization Cellular Protein Complex Assembly Organelle Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Cell Cycle Process Microtubule Nucleation Cellular Component Assembly Cellular Macromolecular Complex Assembly Microtubule Polymerization Mitotic Cell Cycle Process Protein Complex Assembly Mitotic Cell Cycle Microtubule Polymerization Or Depolymerization Centrosome Organization Microtubule Organizing Center Organization Organelle Assembly Regulation Of Protein Stability Centrosome Cycle 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell Division Movement Of Cell Or Subcellular Component Regulation Of Centriole Replication Regulation Of Cell Cycle Process Protein Stabilization Neural Precursor Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cellular Localization Negative Regulation Of Cell Death Spindle Organization Growth Hormone Receptor Signaling Pathway Positive Regulation Of Protein Ubiquitination Cellular Response To Growth Hormone Stimulus Cytoskeleton-dependent Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Centrosome Duplication G2 DNA Damage Checkpoint Neuron Migration Regulation Of Microtubule-based Process Response To Growth Hormone Regulation Of Centrosome Duplication Positive Regulation Of Protein Metabolic Process
Tagcloud ?		1b acetate antioxidant biomarker comparative discovered dosing glatiramer highlighted ifnbeta ikbke insufficiency integrated knowledgebases mediators ms naive nd6 neuropathy nrf2 optic plausible pleiotropic preservation reduces relapsing remitting sclerosis signatures	bipolar dcx disorganization dync1h1 electroporation ganglial gyral inputs interchangeability kif2a kif5c malformations mcd mcds polarization polymicrogyria postmitotic radial rescue round stereotyped tbr2 tuba1a tubb2b tubb3 tubb5 tubulin tubulins utero
Tagcloud (Difference) ?		1b acetate antioxidant biomarker comparative discovered dosing glatiramer highlighted ifnbeta ikbke insufficiency integrated knowledgebases mediators ms naive nd6 neuropathy nrf2 optic plausible pleiotropic preservation reduces relapsing remitting sclerosis signatures	bipolar dcx disorganization dync1h1 electroporation ganglial gyral inputs interchangeability kif2a kif5c malformations mcd mcds polarization polymicrogyria postmitotic radial rescue round stereotyped tbr2 tuba1a tubb2b tubb3 tubb5 tubulin tubulins utero
Tagcloud (Intersection) ?