NCAPH2 and ARLN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NCAPH2	ARLN
Description		non-SMC condensin II complex subunit H2	allregulin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Condensed Nuclear Chromosome Condensin Complex Nucleus Nucleoplasm Chromosome Membrane Cell Junction Intercellular Bridge	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding
	Biological Process	Mitotic Chromosome Condensation Female Meiotic Nuclear Division Meiotic Chromosome Condensation Chromosome Condensation T Cell Differentiation In Thymus Mitotic Sister Chromatid Separation Female Meiosis Chromosome Separation Positive Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Separation Positive Regulation Of Chromosome Condensation
Pathways		Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS		B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cerebrospinal fluid clusterin levels ( 26545630) Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 20139978 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell traits ( 23222517) Serum metabolite levels ( 33031748)
Interacting Genes		27 interacting genes: ACTN2 ANKRD46 APOD ARLN CTXN3 DYRK1A EGLN3 EMD FDFT1 FOLR1 IGFBP5 LMO2 MAL ODAD4 PLK1 PRPF31 SNRPC SUMO2 TMEM120B TMEM14C TMEM86A TRAF2 TTC32 TUBB UBIAD1 USHBP1 VAMP5	73 interacting genes: ADGRG3 AQP2 AQP6 ARL13B ATP2A2 BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 EBP ELN ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 GPX8 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PLN PTGES REEP4 RETREG3 RHBDL1 RHCG SCN3B SERINC2 SHISAL1 SLC10A6 SLC14A2 SLC19A3 SLC35E3 SLC35H1 SLC39A2 SLC41A3 SLC71A2 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A
Entrez ID		29781	401152
HPRD ID		11783	14223
Ensembl ID		ENSG00000025770	ENSG00000164096
Uniprot IDs		Q6IBW4	Q8WVX3
PDB IDs
Enriched GO Terms of Interacting Partners?		Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups	Membrane Transmembrane Transport Protein Binding Plasma Membrane Calcium Ion-transporting ATPase Complex Endoplasmic Reticulum Membrane G Protein-coupled Receptor Activity Connexin Complex Regulation Of Heart Rate Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity One-carbon Compound Transport Carbon Dioxide Transmembrane Transport Gap Junction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Action Potential Transporter Inhibitor Activity SA Node Cell Action Potential Transmembrane Transporter Binding Mitochondrion-endoplasmic Reticulum Membrane Tethering Regulation Of Cardiac Muscle Cell Membrane Potential Autophagosome Membrane Docking Regulation Of Cardiac Muscle Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization G Protein-coupled Receptor Signaling Pathway Renal Water Transport Regulation Of System Process Ammonium Channel Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Ammonium Transmembrane Transport Regulation Of Blood Circulation Calcium-mediated Signaling Metal Ion Transport Regulation Of Striated Muscle Contraction
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