NCAPH2 and FOLR1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NCAPH2	FOLR1
Gene Name		non-SMC condensin II complex, subunit H2	folate receptor 1 (adult)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome Membrane	Endosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Clathrin-coated Vesicle Anchored Component Of External Side Of Plasma Membrane Brush Border Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Receptor Activity Folic Acid Binding Folic Acid Transporter Activity
	Biological Process	Mitotic Cell Cycle Chromosome Condensation	Receptor-mediated Endocytosis Folic Acid Transport Folic Acid Metabolic Process
Pathways		Mitotic Prophase Condensation of Prophase Chromosomes Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		5 interactors: EGLN3 FOLR1 LMO2 SNRPC USHBP1	4 interactors: CUL3 IRAK3 LYN NCAPH2
Entrez ID		29781	2348
HPRD ID		11783	00638
Ensembl ID		ENSG00000025770	ENSG00000110195
Uniprot IDs		Q6IBW4	P15328
PDB IDs			4KM6 4KM7 4KMX 4LRH
Enriched GO Terms of Interacting Partners?		MRNA 5'-splice Site Recognition Cellular Modified Amino Acid Metabolic Process Alpha-amino Acid Metabolic Process Folic Acid Transport Negative Regulation Of Erythrocyte Differentiation Heterocycle Metabolic Process Cellular Response To Thyroid Hormone Stimulus Folic Acid Metabolic Process MRNA Transcription From RNA Polymerase II Promoter Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Cellular Amino Acid Metabolic Process MRNA Transcription Response To Thyroid Hormone MRNA Cis Splicing, Via Spliceosome Nitrogen Compound Metabolic Process 4-hydroxyproline Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Peptidyl-proline Hydroxylation Protein Hydroxylation Embryonic Hemopoiesis Regulation Of Erythrocyte Differentiation Cofactor Transport Spliceosomal SnRNP Assembly MRNA Splice Site Selection	Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of MAP Kinase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Oligodendrocyte Progenitor Proliferation Positive Regulation Of Macrophage Tolerance Induction Negative Regulation Of Mast Cell Proliferation Negative Regulation Of Immune Response Negative Regulation Of Protein Metabolic Process Negative Regulation Of MAPK Cascade Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Protein Autophosphorylation Tolerance Induction To Self Antigen Fc Receptor Mediated Inhibitory Signaling Pathway Trophectodermal Cellular Morphogenesis Positive Regulation Of Dendritic Cell Apoptotic Process Negative Regulation Of Signaling Negative Regulation Of Macrophage Cytokine Production Regulation Of Phosphorylation Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Regulation Of MAP Kinase Activity Immune Response-inhibiting Signal Transduction Regulation Of Phosphorus Metabolic Process Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Tolerance Induction Positive Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Mast Cell Proliferation Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Immune System Process Regulation Of Oligodendrocyte Progenitor Proliferation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Protein Catabolic Process Organelle Localization
Tagcloud ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?