GSTM5 and GPKOW

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GSTM5	GPKOW
Description		glutathione S-transferase mu 5	G-patch domain and KOW motifs
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	Glutathione Transferase Activity Protein Binding Transferase Activity Identical Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Glutathione Metabolic Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		Glutathione conjugation	mRNA Splicing - Major Pathway
Drugs		Glutathione Glutathione disulfide Deoxycholic acid
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		3 interacting genes: AMOTL2 CDC42 GPKOW	47 interacting genes: APP ARMCX1 BUD13 CCDC57 CNKSR3 DDIT4L EFHC2 FBXO7 GMPPA GOLGA2 GSTM5 HOOK2 HSF2BP IKBKG KANK2 LNX1 LRP2BP LZTS1 MAD1L1 MEOX2 MESD MID2 MTUS2 NINL OGT PHF1 PIBF1 PICK1 POLR2G PPP1CA PRKAR1B PRPF4 PRPF8 REL ROPN1 SH3GL1 SORBS3 SPDYE4 TCEA1 TCEA2 TRAF2 TRIM23 TRIM27 VPS52 WDR77 WDR83 ZMYND12
Entrez ID		2949	27238
HPRD ID		00711	06737
Ensembl ID		ENSG00000134201	ENSG00000068394
Uniprot IDs		P46439 Q5T8R1 Q5T8R2	Q92917
PDB IDs			7DVQ 7QTT 8CH6
Enriched GO Terms of Interacting Partners?		Wnt Signaling Pathway Apolipoprotein A-I Receptor Binding Endothelin Receptor Signaling Pathway Involved In Heart Process Establishment Of Cell Polarity Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Establishment Or Maintenance Of Cell Polarity Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Leading Edge Membrane Thioesterase Binding Actin Filament-based Process Positive Regulation Of Pinocytosis Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Neuron Fate Determination Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Establishment Of Golgi Localization Actin Cytoskeleton Organization Golgi Transport Complex Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Golgi Localization Endothelial Cell Morphogenesis Cardiac Conduction System Development Establishment Of Epithelial Cell Apical/basal Polarity Cell Migration Involved In Heart Development Dendritic Spine Morphogenesis Regulation Of Attachment Of Spindle Microtubules To Kinetochore Establishment Of Apical/basal Cell Polarity Dendritic Cell Migration Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction Embryonic Heart Tube Development Filopodium Assembly Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Positive Regulation Of Lamellipodium Assembly Spindle Midzone Nuclear Migration Hippo Signaling Establishment Of Epithelial Cell Polarity Positive Regulation Of Filopodium Assembly Phagocytosis, Engulfment Nucleus Localization Heart Process Dendritic Spine Organization Positive Regulation Of Lamellipodium Organization	Cytoplasm Protein Binding Identical Protein Binding Regulation Of Autophagy Positive Regulation Of Autophagy
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