GSTM5

Gene Name		glutathione S-transferase mu 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Glutathione Transferase Activity
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Small Molecule Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: AMOTL2 GSTM3
Entrez ID		2949
HPRD ID		00711
Ensembl ID		ENSG00000134201
Uniprot IDs		P46439 Q5T8R2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Detoxification Of Nitrogen Compound Nitrobenzene Metabolic Process Detoxification Of Nitrogen Compound Establishment Of Blood-nerve Barrier Xenobiotic Catabolic Process Glutathione Derivative Biosynthetic Process Hippo Signaling Endothelial Cell Development Glutathione Metabolic Process Endothelial Cell Differentiation Endothelium Development Peripheral Nervous System Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Peptide Metabolic Process Response To Toxic Substance
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