GSC2 and GALNT11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GSC2	GALNT11
Description		goosecoid homeobox 2	polypeptide N-acetylgalactosaminyltransferase 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Notch Binding Protein Binding Transferase Activity Glycosyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis	Protein Glycosylation Protein O-linked Glycosylation Notch Signaling Pathway Notch Receptor Processing Determination Of Left/right Symmetry Regulation Of Notch Signaling Pathway Protein O-linked Glycosylation Via N-acetyl-galactosamine Cilium Assembly Notch Signaling Involved In Heart Development
Pathways			O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Metabolite levels ( 22916037)	Kidney function decline traits ( 25493955) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		60 interacting genes: ALPP ANXA5 ASPH BEST3 BNIP2 C19orf47 C1D CALM1 CALM2 CALM3 CALR CDKN2D CIAO2A COL8A1 CRCP CSNK2A1 DYRK1B EGLN3 EIF5A ETFDH FAM221B FKBP6 GALNT11 GCM2 GTF2H5 GTSF1L GUCA1A GUCY1A2 HMBOX1 ISX KDM6A KLHL38 KRT34 KRTAP5-9 LCE3E LTO1 MAD2L2 MAPK9 MARF1 MID2 MORF4L1 MRPL53 MRPS23 NME7 PACSIN2 PDE4C PRKAB2 PTER RNF4 SCAF1 SDCBP TIPIN TNPO2 TSR2 UBE2R2 VCX2 XRCC4 YPEL5 ZNF444 ZNF587	3 interacting genes: GSC2 MUC4 SGTB
Entrez ID		2928	63917
HPRD ID		03506	13560
Ensembl ID		ENSG00000063515	ENSG00000178234
Uniprot IDs		O15499	A0A090N7X6 B7Z5G5 Q8NCW6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Communication By Electrical Coupling Detection Of Calcium Ion Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Calcium Channel Complex Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of High Voltage-gated Calcium Channel Activity Titin Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity DNA Metabolic Process Response To Metal Ion Protein Phosphatase Activator Activity Calyx Of Held Protein Binding Catalytic Complex Negative Regulation Of Transporter Activity Response To Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cardiac Muscle Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Striated Muscle Contraction DNA Damage Response Spindle Microtubule Negative Regulation Of Monoatomic Ion Transport Nucleic Acid Metabolic Process Presynaptic Endocytosis Substantia Nigra Development Sarcoplasmic Reticulum Lumen Calcium Channel Regulator Activity Detection Of Chemical Stimulus Sperm Midpiece Adenylate Cyclase Binding Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Nucleobase-containing Compound Metabolic Process	ErbB-2 Class Receptor Binding Extracellular Matrix Constituent, Lubricant Activity TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
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