GALNT11 and MUC4

Number of citations of the paper that reports this interaction (PMID 11925450)
34

Data Source:
HPRD (in vitro)

		GALNT11	MUC4
Gene Name		polypeptide N-acetylgalactosaminyltransferase 11	mucin 4, cell surface associated
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Proteinaceous Extracellular Matrix Extracellular Space Golgi Lumen Integral Component Of Plasma Membrane Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Notch Binding Carbohydrate Binding Metal Ion Binding	ErbB-2 Class Receptor Binding Extracellular Matrix Constituent, Lubricant Activity
	Biological Process	Protein O-linked Glycosylation Notch Receptor Processing Determination Of Left/right Symmetry Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Glycosylation Via Threonine Post-translational Protein Modification Cellular Protein Metabolic Process Cilium Morphogenesis Notch Signaling Involved In Heart Development	Protein O-linked Glycosylation Cell-matrix Adhesion O-glycan Processing Maintenance Of Gastrointestinal Epithelium Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Post-translational protein modification O-linked glycosylation of mucins O-linked glycosylation	Post-translational protein modification Termination of O-glycan biosynthesis O-linked glycosylation of mucins O-linked glycosylation
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: MUC4	2 interactors: ERBB2 GALNT11
Entrez ID		63917	4585
HPRD ID		13560	11829
Ensembl ID		ENSG00000178234	ENSG00000145113
Uniprot IDs		B3KWF4 B7Z5G5 Q8NCW6	A0T3F4 E9PDY6 Q99102
PDB IDs
Enriched GO Terms of Interacting Partners?		Maintenance Of Gastrointestinal Epithelium Epithelial Structure Maintenance O-glycan Processing Protein O-linked Glycosylation Digestion Hematopoietic Progenitor Cell Differentiation Cell-matrix Adhesion Tissue Homeostasis Post-translational Protein Modification Cell-substrate Adhesion Multicellular Organismal Homeostasis Macromolecule Glycosylation Protein Glycosylation Glycosylation	Negative Regulation Of Immature T Cell Proliferation In Thymus Protein O-linked Glycosylation Via Threonine Heart Development Negative Regulation Of T Cell Differentiation In Thymus Notch Signaling Involved In Heart Development Positive Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase I Promoter Cell Projection Morphogenesis Cell Part Morphogenesis Cardiovascular System Development Regulation Of Transcription From RNA Polymerase I Promoter Peptidyl-amino Acid Modification Regulation Of Transcription From RNA Polymerase III Promoter Notch Receptor Processing Phosphatidylinositol 3-kinase Signaling Cell Morphogenesis Cell Projection Organization Regulation Of T Cell Differentiation In Thymus Motor Neuron Axon Guidance Negative Regulation Of T Cell Differentiation Negative Regulation Of Lymphocyte Differentiation O-glycan Processing Neuromuscular Junction Development Negative Regulation Of T Cell Proliferation Regulation Of Notch Signaling Pathway Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Positive Regulation Of Translation Oligodendrocyte Differentiation Protein O-linked Glycosylation Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion
Tagcloud ?			bc circumvent critically dm1 dramatic efforts emerging expanding exploit family her2 holds immunity improvements overexpress p27kip1 p95her2 pan pi3k positivity pten repertoire rtk rtks signalling targeted therapies trastuzumab worse
Tagcloud (Difference) ?			bc circumvent critically dm1 dramatic efforts emerging expanding exploit family her2 holds immunity improvements overexpress p27kip1 p95her2 pan pi3k positivity pten repertoire rtk rtks signalling targeted therapies trastuzumab worse
Tagcloud (Intersection) ?