NCOA3 and ESRRB

Number of citations of the paper that reports this interaction (PMID 10598588)
26

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		NCOA3	ESRRB
Gene Name		nuclear receptor coactivator 3	estrogen-related receptor beta
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Signal Transducer Activity Protein Binding Ligand-dependent Nuclear Receptor Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Nuclear Hormone Receptor Binding Thyroid Hormone Receptor Binding Protein Dimerization Activity Protein N-terminus Binding Androgen Receptor Binding	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Steroid Hormone Receptor Activity Transcription Coactivator Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Steroid Binding Transcription Factor Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Gene Expression Histone Acetylation Androgen Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Cellular Response To Hormone Stimulus Multicellular Organism Growth Receptor Transactivation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Developmental Growth Vagina Development Labyrinthine Layer Morphogenesis Mammary Gland Branching Involved In Thelarche Regulation Of RNA Biosynthetic Process	Trophectodermal Cellular Morphogenesis Trophectodermal Cell Proliferation Embryonic Placenta Development Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Response to treatment for acute lymphoblastic leukemia ( 19176441)
Protein-Protein Interactions		77 interactors: ABL1 ANKRD11 AR ARNT2 ATAD2 BMP6 BMP7 BRCA1 BRE CCND1 CDKN3 CHUK CREBBP CSNK1E DCTN6 DDX17 DDX5 E2F1 EP300 ESR1 ESR2 ESRRA ESRRB ETV1 FOS GSK3B GTF2B HIST3H3 HIST4H4 IKBKB IKBKG IQCK JUN KAT2B MAPK1 MAPK14 MAPK8 MMS19 MN1 NCOR1 NCOR2 NKX2-1 NPAS2 NR0B2 NR1H2 NR1H3 NR1I2 NR1I3 NR2F1 NR3C1 NR4A1 NR5A2 PGR PIN1 PPARA PPARD PPARG PRKCZ PRMT1 PSMB9 PSME3 RARA RARB RARG RELA RXRA RXRB SMARCE1 SUFU SUMO1 TBP THRB TP53 TP53BP1 VDR YWHAH YWHAQ	5 interactors: DPF2 NCOA2 NCOA3 NRIP1 SP1
Entrez ID		8202	2103
HPRD ID		03570	03700
Ensembl ID		ENSG00000124151	ENSG00000119715
Uniprot IDs		Q0IIN7 Q59EE8 Q9Y6Q9	O95718
PDB IDs		1KBH 3L3X 3L3Z	1LO1
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Hormone-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Response To Steroid Hormone Response To Lipid Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Response To Lipid Regulation Of Gene Expression Response To Hormone Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Cellular Response To Organic Cyclic Compound Cellular Response To Organic Substance Transcription, DNA-templated Response To Organic Substance RNA Biosynthetic Process Regulation Of Metabolic Process Cellular Response To Hormone Stimulus Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Gene Expression Negative Regulation Of RNA Biosynthetic Process Signaling Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cell Communication Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process	Intracellular Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Androgen Receptor Signaling Pathway Positive Regulation Of Receptor Activity Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Reproductive Structure Development Intracellular Steroid Hormone Receptor Signaling Pathway Reproductive System Development Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Circadian Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Sequestering Of Nodal From Receptor Via Nodal Binding Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Acetylation Embryonic Placenta Development Regulation Of Receptor Activity Regulation Of RNA Metabolic Process Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Developmental Process Involved In Reproduction Nucleobase-containing Compound Metabolic Process Protein Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Ovarian Follicle Rupture Negative Regulation Of Nodal Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Circadian Rhythm Signal Transduction Positive Regulation Of Cellular Metabolic Process Placenta Development Nitrogen Compound Metabolic Process Signaling Cell Communication Receptor Transactivation
Tagcloud ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 overlap progenitor progenitors proliferative tale tif2 translocations	accord argue assigns autocrine backgroundthe behind circuit conclusionswe crosstalks empirically feedbacks fgf fluctuating fluctuations inverted jointly klf4 loops mark markon nanog oct4 operates phosphorilation pluripotency question resultsas sox2 testable
Tagcloud (Difference) ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 overlap progenitor progenitors proliferative tale tif2 translocations	accord argue assigns autocrine backgroundthe behind circuit conclusionswe crosstalks empirically feedbacks fgf fluctuating fluctuations inverted jointly klf4 loops mark markon nanog oct4 operates phosphorilation pluripotency question resultsas sox2 testable
Tagcloud (Intersection) ?