CLCN7 and OSTM1

Number of citations of the paper that reports this interaction (PMID 16525474)
41

Data Source:
HPRD (in vivo)

		CLCN7	OSTM1
Gene Name		chloride channel, voltage-sensitive 7	osteopetrosis associated transmembrane protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle	Nucleus Cytoplasm Lysosomal Membrane Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity ATP Binding Antiporter Activity
	Biological Process	Transport Response To PH Ion Transmembrane Transport Regulation Of Anion Transport Transmembrane Transport Chloride Transmembrane Transport	Osteoclast Differentiation Ion Transmembrane Transport Transmembrane Transport
Pathways		Ion channel transport Stimuli-sensing channels	Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: OSTM1 PACS1	6 interactors: CLCN7 GPSM1 LIG4 RGS17 RGS19 RGS20
Entrez ID		1186	28962
HPRD ID		04103	09628
Ensembl ID		ENSG00000103249	ENSG00000081087
Uniprot IDs		P51798	Q86WC4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Targeting To Golgi Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Defense Response To Virus By Virus Protein Localization To Golgi Apparatus Protein Targeting To Plasma Membrane Osteoclast Differentiation Intra-Golgi Vesicle-mediated Transport Establishment Of Protein Localization To Plasma Membrane Regulation Of Defense Response To Virus	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway DNA Ligation Involved In DNA Recombination Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Regulation Of Catalytic Activity Lagging Strand Elongation Pro-B Cell Differentiation Positive Regulation Of Hydrolase Activity Negative Regulation Of Signal Transduction Establishment Of Integrated Proviral Latency Negative Regulation Of Signaling Establishment Of Viral Latency Immunoglobulin V(D)J Recombination Regulation Of Signal Transduction DNA Ligation Involved In DNA Repair T Cell Receptor V(D)J Recombination Lymphoid Progenitor Cell Differentiation Regulation Of Signaling DNA Ligation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Positive Regulation Of Catalytic Activity Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Response To Lithium Ion DNA Strand Elongation Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Response To PH Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Response To Gamma Radiation Neuron Apoptotic Process
Tagcloud ?		apply asp complementation complementing ddx1 disequilibrium erb ercc1 erythroblastic exo1 exonuclease gwas helicase inconsistent nominal perfect phosphoprotein prerequisite reexamined replicate replicating rs2844484 rs2857602 spp1 stringent swedish tmc6 tmc8 underscore	anhydrase arthritis carbonic cathepsin chalcone clcn7 destructive elucidate expressions fos gab2 modulating multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts osteoporosis periodontitis pit prenylated rankl raw264 resorption structurally suppress tcirg traf6 xanthohumol
Tagcloud (Difference) ?		apply asp complementation complementing ddx1 disequilibrium erb ercc1 erythroblastic exo1 exonuclease gwas helicase inconsistent nominal perfect phosphoprotein prerequisite reexamined replicate replicating rs2844484 rs2857602 spp1 stringent swedish tmc6 tmc8 underscore	anhydrase arthritis carbonic cathepsin chalcone destructive elucidate expressions fos gab2 modulating multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts osteoporosis periodontitis pit prenylated rankl raw264 resorption structurally suppress tcirg traf6 xanthohumol
Tagcloud (Intersection) ?		clcn7