NOA1 and AIFM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		NOA1	AIFM1
Gene Name		nitric oxide associated 1	apoptosis-inducing factor, mitochondrion-associated, 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Extrinsic Component Of Mitochondrial Inner Membrane	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding	DNA Binding Protein Binding Electron Carrier Activity NAD(P)H Oxidase Activity Oxidoreductase Activity, Acting On NAD(P)H Protein Dimerization Activity FAD Binding
	Biological Process	Apoptotic Process Regulation Of Cell Death Mitochondrial Translation Ribosome Biogenesis Regulation Of Cellular Respiration	DNA Catabolic Process Apoptotic DNA Fragmentation Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Neuron Differentiation Chromosome Condensation Mitochondrial Respiratory Chain Complex I Assembly Positive Regulation Of Apoptotic Process Cell Redox Homeostasis Neuron Apoptotic Process Oxidation-reduction Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Apoptotic DNA Fragmentation
Pathways
Drugs			Flavin-Adenine Dinucleotide
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ABCB8 ABCF3 AIFM1 ARF1 BOK COL9A2 DCTPP1 GRB10 H1F0 HSPA8 MPP3 NFU1 WDR18	11 interactors: CASP3 EIF3G HSPA1A HSPA1B MLH1 NOA1 SETDB1 STC2 TSC22D4 WWC1 XIAP
Entrez ID		84273	9131
HPRD ID		12823	02161
Ensembl ID			ENSG00000156709
Uniprot IDs		Q8NC60	O95831
PDB IDs			1M6I 4FDC 4LII
Enriched GO Terms of Interacting Partners?		Apoptotic DNA Fragmentation Regulation Of Execution Phase Of Apoptosis Apoptotic Nuclear Changes Neuron Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Fibril Organization Neuron Death Execution Phase Of Apoptosis Post-Golgi Vesicle-mediated Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process DNA Catabolic Process, Endonucleolytic Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Regulation Of Fibril Organization Aromatic Compound Catabolic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity DNA Catabolic Process Clathrin Coat Disassembly Positive Regulation Of Peptidase Activity Regulation Of Apoptotic DNA Fragmentation	Negative Regulation Of Cellular Metabolic Process Cellular Heat Acclimation Negative Regulation Of Growth Regulation Of Metabolic Process Negative Regulation Of Inclusion Body Assembly Gene Expression Cellular Response To Stress Response To Unfolded Protein Response To Oxidative Stress Regulation Of Inclusion Body Assembly Aromatic Compound Catabolic Process Protein Refolding Positive Regulation Of Erythrocyte Differentiation MRNA Catabolic Process RNA Catabolic Process Response To Abiotic Stimulus Intrinsic Apoptotic Signaling Pathway Hippo Signaling Regulation Of Cellular Response To Heat Cellular Response To Oxidative Stress Regulation Of Protein Ubiquitination Regulation Of Growth Regulation Of Erythrocyte Differentiation Viral Entry Into Host Cell Entry Into Host Cell Response To Stress Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cell Death Cellular Response To Heat Cellular Macromolecule Catabolic Process Apoptotic Signaling Pathway Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Process Negative Regulation Of Apoptotic Process Positive Regulation Of Myeloid Cell Differentiation Negative Regulation Of Programmed Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Process Negative Regulation Of Developmental Growth Negative Regulation Of Cell Death Protein Stabilization Programmed Cell Death Positive Regulation Of Protein Linear Polyubiquitination Negative Regulation Of Mitotic Recombination Cell Death Death Negative Regulation Of Protein Ubiquitination
Tagcloud ?			agilent antiproliferative biologically cables2 ccnk cdc25b cdca3 cdca8 cnnm3 constituents cytometric dmso emge ginseng ginsenosides hepatocarcinoma hepg2 hspa9 ic50 metabolized mu panax ppt primeview rg3 rh1 saponin saponins uqcrc2
Tagcloud (Difference) ?			agilent antiproliferative biologically cables2 ccnk cdc25b cdca3 cdca8 cnnm3 constituents cytometric dmso emge ginseng ginsenosides hepatocarcinoma hepg2 hspa9 ic50 metabolized mu panax ppt primeview rg3 rh1 saponin saponins uqcrc2
Tagcloud (Intersection) ?